mTOR Modulation of <i>I<sub>Kr</sub></i> through hERG1b-Dependent Mechanisms in Lipotoxic Heart

In the atria, the rapid delayed rectifier channel (<i>I<sub>Kr</sub></i>) is a critical contributor to repolarization. In lipotoxic atria, increased activity of the serine/threonine mammalian target of rapamycin (mTOR) may remodel <i>I<sub>Kr</sub></i>...

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Bibliographic Details
Main Authors: Kelly A. Aromolaran, Jenny Do, Joyce Bernardi, Ademuyiwa S. Aromolaran
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/15/8061