Epstein–Barr virus mucocutaneous ulcer followed by Hodgkin lymphoma in multiple myeloma patient

Abstract Epstein–Barr virus mucocutaneous ulcers (EBV MCU) are B‐cell lymphoproliferative disorders associated with immunosuppression. We report EBV MCU in a multiple myeloma patient on lenalidomide maintenance after stem cell transplant that resolved with decreased immunosuppression. Furthermore, t...

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Main Authors: Moriah Forster, Yuri Fedoriw, Sascha Tuchman, Natalie Grover
Format: Article
Language:English
Published: Wiley 2022-03-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.5528
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author Moriah Forster
Yuri Fedoriw
Sascha Tuchman
Natalie Grover
author_facet Moriah Forster
Yuri Fedoriw
Sascha Tuchman
Natalie Grover
author_sort Moriah Forster
collection DOAJ
description Abstract Epstein–Barr virus mucocutaneous ulcers (EBV MCU) are B‐cell lymphoproliferative disorders associated with immunosuppression. We report EBV MCU in a multiple myeloma patient on lenalidomide maintenance after stem cell transplant that resolved with decreased immunosuppression. Furthermore, the subsequent development of classical Hodgkin lymphoma suggests an underlying predisposition to EBV‐driven lymphoproliferative disorders.
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spelling doaj.art-0e79a559c4a94232893d3314a96949652022-12-21T21:18:49ZengWileyClinical Case Reports2050-09042022-03-01103n/an/a10.1002/ccr3.5528Epstein–Barr virus mucocutaneous ulcer followed by Hodgkin lymphoma in multiple myeloma patientMoriah Forster0Yuri Fedoriw1Sascha Tuchman2Natalie Grover3Department of Internal Medicine University of North Carolina Chapel Hill North Carolina USADepartment of Pathology and Lab Medicine University of North Carolina Chapel Hill North Carolina USALineberger Comprehensive Cancer Center Department of Hematology University of North Carolina Chapel Hill North Carolina USALineberger Comprehensive Cancer Center Department of Hematology University of North Carolina Chapel Hill North Carolina USAAbstract Epstein–Barr virus mucocutaneous ulcers (EBV MCU) are B‐cell lymphoproliferative disorders associated with immunosuppression. We report EBV MCU in a multiple myeloma patient on lenalidomide maintenance after stem cell transplant that resolved with decreased immunosuppression. Furthermore, the subsequent development of classical Hodgkin lymphoma suggests an underlying predisposition to EBV‐driven lymphoproliferative disorders.https://doi.org/10.1002/ccr3.5528diagnostic dilemmaEpstein–Barr VirusHodgkin Lymphomaimmunosuppressionlenalidomidemucocutaneous ulcer
spellingShingle Moriah Forster
Yuri Fedoriw
Sascha Tuchman
Natalie Grover
Epstein–Barr virus mucocutaneous ulcer followed by Hodgkin lymphoma in multiple myeloma patient
Clinical Case Reports
diagnostic dilemma
Epstein–Barr Virus
Hodgkin Lymphoma
immunosuppression
lenalidomide
mucocutaneous ulcer
title Epstein–Barr virus mucocutaneous ulcer followed by Hodgkin lymphoma in multiple myeloma patient
title_full Epstein–Barr virus mucocutaneous ulcer followed by Hodgkin lymphoma in multiple myeloma patient
title_fullStr Epstein–Barr virus mucocutaneous ulcer followed by Hodgkin lymphoma in multiple myeloma patient
title_full_unstemmed Epstein–Barr virus mucocutaneous ulcer followed by Hodgkin lymphoma in multiple myeloma patient
title_short Epstein–Barr virus mucocutaneous ulcer followed by Hodgkin lymphoma in multiple myeloma patient
title_sort epstein barr virus mucocutaneous ulcer followed by hodgkin lymphoma in multiple myeloma patient
topic diagnostic dilemma
Epstein–Barr Virus
Hodgkin Lymphoma
immunosuppression
lenalidomide
mucocutaneous ulcer
url https://doi.org/10.1002/ccr3.5528
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AT saschatuchman epsteinbarrvirusmucocutaneousulcerfollowedbyhodgkinlymphomainmultiplemyelomapatient
AT nataliegrover epsteinbarrvirusmucocutaneousulcerfollowedbyhodgkinlymphomainmultiplemyelomapatient