An aneurysmal bone cyst at T1 treated with bone grafts containing calcitonin and methylprednisolone

Aneurysmal bone cysts (ABCs) rarely trigger pathological fractures. Various surgical and nonsurgical treatments have been reported for this condition. Herein, we present the examination findings and treatment for a 15-year-old girl who initially presented with adolescent idiopathic scoliosis and mil...

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Main Authors: Akinori Okuda, Hideki Shigematsu, Eiichiro Iwata, Masato Tanaka, Yasuhiko Morimoto, Keisuke Masuda, Chiho Ohbayashi, Yasuhito Tanaka
Format: Article
Language:English
Published: SAGE Publishing 2019-04-01
Series:Journal of Orthopaedic Surgery
Online Access:https://doi.org/10.1177/2309499019839626
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author Akinori Okuda
Hideki Shigematsu
Eiichiro Iwata
Masato Tanaka
Yasuhiko Morimoto
Keisuke Masuda
Chiho Ohbayashi
Yasuhito Tanaka
author_facet Akinori Okuda
Hideki Shigematsu
Eiichiro Iwata
Masato Tanaka
Yasuhiko Morimoto
Keisuke Masuda
Chiho Ohbayashi
Yasuhito Tanaka
author_sort Akinori Okuda
collection DOAJ
description Aneurysmal bone cysts (ABCs) rarely trigger pathological fractures. Various surgical and nonsurgical treatments have been reported for this condition. Herein, we present the examination findings and treatment for a 15-year-old girl who initially presented with adolescent idiopathic scoliosis and mild back pain, but subsequently experienced severe back pain. Magnetic resonance imaging revealed an ABC at T1, with an associated pathological fracture. We successfully treated the patient using posterior fixation with instrumentation, curettage, and bone grafts combined with calcitonin and methylprednisolone (mPSL). At 3 years post-surgery, there was no ABC recurrence and only mild back pain persisted. To our knowledge, this is the first report of open surgery (curettage and fixation) with local intralesional administration of calcitonin and mPSL for an ABC-induced pathological spinal fracture. We believe that this treatment is an effective option for ABCs associated with a pathological spinal fracture.
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spelling doaj.art-0e7a45dd40624d988c18a8851c5fc5562022-12-21T19:04:53ZengSAGE PublishingJournal of Orthopaedic Surgery2309-49902019-04-012710.1177/2309499019839626An aneurysmal bone cyst at T1 treated with bone grafts containing calcitonin and methylprednisoloneAkinori Okuda0Hideki Shigematsu1Eiichiro Iwata2Masato Tanaka3Yasuhiko Morimoto4Keisuke Masuda5Chiho Ohbayashi6Yasuhito Tanaka7 Department of Orthopedic Surgery, Nara Medical University, Kashihara, Japan Department of Orthopedic Surgery, Nara Medical University, Kashihara, Japan Department of Orthopedic Surgery, Nara Medical University, Kashihara, Japan Department of Orthopedic Surgery, Nara Medical University, Kashihara, Japan Department of Orthopedic Surgery, Nara Medical University, Kashihara, Japan Department of Orthopedic Surgery, Nara Medical University, Kashihara, Japan Department of Diagnostic Pathology, Nara Medical University, Kashihara, Japan Department of Orthopedic Surgery, Nara Medical University, Kashihara, JapanAneurysmal bone cysts (ABCs) rarely trigger pathological fractures. Various surgical and nonsurgical treatments have been reported for this condition. Herein, we present the examination findings and treatment for a 15-year-old girl who initially presented with adolescent idiopathic scoliosis and mild back pain, but subsequently experienced severe back pain. Magnetic resonance imaging revealed an ABC at T1, with an associated pathological fracture. We successfully treated the patient using posterior fixation with instrumentation, curettage, and bone grafts combined with calcitonin and methylprednisolone (mPSL). At 3 years post-surgery, there was no ABC recurrence and only mild back pain persisted. To our knowledge, this is the first report of open surgery (curettage and fixation) with local intralesional administration of calcitonin and mPSL for an ABC-induced pathological spinal fracture. We believe that this treatment is an effective option for ABCs associated with a pathological spinal fracture.https://doi.org/10.1177/2309499019839626
spellingShingle Akinori Okuda
Hideki Shigematsu
Eiichiro Iwata
Masato Tanaka
Yasuhiko Morimoto
Keisuke Masuda
Chiho Ohbayashi
Yasuhito Tanaka
An aneurysmal bone cyst at T1 treated with bone grafts containing calcitonin and methylprednisolone
Journal of Orthopaedic Surgery
title An aneurysmal bone cyst at T1 treated with bone grafts containing calcitonin and methylprednisolone
title_full An aneurysmal bone cyst at T1 treated with bone grafts containing calcitonin and methylprednisolone
title_fullStr An aneurysmal bone cyst at T1 treated with bone grafts containing calcitonin and methylprednisolone
title_full_unstemmed An aneurysmal bone cyst at T1 treated with bone grafts containing calcitonin and methylprednisolone
title_short An aneurysmal bone cyst at T1 treated with bone grafts containing calcitonin and methylprednisolone
title_sort aneurysmal bone cyst at t1 treated with bone grafts containing calcitonin and methylprednisolone
url https://doi.org/10.1177/2309499019839626
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