P2X7 receptor inhibition ameliorates dendritic spine pathology and social behavioral deficits in Rett syndrome mice

P2X7 receptor inhibition ameliorates dendritic spine pathology and social behavioral deficits in Rett syndrome mice

P2X7 receptors are purinergic receptors with pro-inflammatory functions. Here, the authors show that inhibition of leukocyte P2X7 receptors reduces dendritic spine pathology and social behavioral deficits in a mouse model of Rett syndrome.

Bibliografiske detaljer
Main Authors:	Juan Mauricio Garré, Hernandez Moura Silva, Juan J. Lafaille, Guang Yang
Format:	Article
Sprog:	English
Udgivet:	Nature Portfolio 2020-04-01
Serier:	Nature Communications
Online adgang:	https://doi.org/10.1038/s41467-020-15590-5

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