Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care
INTRODUCTION: increased survival of preterm babies in sub-saharan Africa has held to an increasing prevalence of Retinopathy of prematurity (ROP). This study was done to determine the ROP prevalence in a hospital with advanced neonatal care in urban Kenya. METHODS: a hospital-based retrospective rev...
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| Format: | Article |
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The Pan African Medical Journal
2018-03-01
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| Series: | The Pan African Medical Journal |
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https://www.panafrican-med-journal.com/content/article/29/152/pdf/152.pdf
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| author | Oscar Onyango Sarah Sitati Lucia Amolo Florence Murila Susan Wariua Gacheri Nyamu Moses Lango Atul Patel |
| author_facet | Oscar Onyango Sarah Sitati Lucia Amolo Florence Murila Susan Wariua Gacheri Nyamu Moses Lango Atul Patel |
| author_sort | Oscar Onyango |
| collection | DOAJ |
| description | INTRODUCTION: increased survival of preterm babies in sub-saharan Africa has held to an increasing prevalence of Retinopathy of prematurity (ROP). This study was done to determine the ROP prevalence in a hospital with advanced neonatal care in urban Kenya. METHODS: a hospital-based retrospective review of the records of premature infants screened for ROP between January 2010 and December 2015. Records of all premature infants screened for ROP in the neonatal unit and outpatient eye clinic were extracted. Information on Birth weights, Gestational age, Maternal risk factors (mode of delivery, pre-eclampsia/eclampsia) and Neonatal risk factors (neonatal sepsis, days on oxygen, blood transfusion) was recorded in a questionnaire then analysed. RESULTS: 103 infants were included in the study. Mean gestational age was 29.9 , 2.2 weeks and the mean birth weight was 1280.1 , 333.0 grams. Forty-three infants were diagnosed with ROP, a prevalence of 41.7%. Majority of these had Stage 1 or 2 ROP in Zone II, which spontaneously regressed with follow up. Nine infants were diagnosed with vision-threatening ROP (any Zone I disease or Stage 2/3 disease in Zone II with plus disease), a prevalence of 20.9%. All of these underwent laser treatment in the neonatal unit. The most significant risk factor was low gestational age. Other risk factors identified were: low birth weight and blood transfusions. CONCLUSION: ROP prevalence in sub-saharan Africa will match those in middle-income and high income countries in neonatal units with advanced care and low mortality. |
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| institution | Directory Open Access Journal |
| issn | 1937-8688 1937-8688 |
| language | English |
| last_indexed | 2024-12-20T00:25:07Z |
| publishDate | 2018-03-01 |
| publisher | The Pan African Medical Journal |
| record_format | Article |
| series | The Pan African Medical Journal |
| spelling | doaj.art-0e85993decba463a93d0cd94bd6a5c622022-12-21T20:00:05ZengThe Pan African Medical JournalThe Pan African Medical Journal1937-86881937-86882018-03-012915210.11604/pamj.2018.29.152.1404614046Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal careOscar Onyango0Sarah Sitati1Lucia Amolo2Florence Murila3Susan Wariua4Gacheri Nyamu5Moses Lango6Atul Patel7 Nairobi Hospital, Department of Ophthalmology, Nairobi, Kenya Sabatia Eye Hospital, Department of Pediatric Ophthalmology, Wodanga, Kenya Nairobi Hospital, Department of Neonatology, Nairobi, Kenya Nairobi Hospital, Department of Neonatology, Nairobi, Kenya Nairobi Hospital, Department of Neonatology, Nairobi, Kenya Nairobi Hospital, Department of Neonatology, Nairobi, Kenya Nairobi Hospital, Department of Neonatology, Nairobi, Kenya Nairobi Hospital, Department of Neonatology, Nairobi, Kenya INTRODUCTION: increased survival of preterm babies in sub-saharan Africa has held to an increasing prevalence of Retinopathy of prematurity (ROP). This study was done to determine the ROP prevalence in a hospital with advanced neonatal care in urban Kenya. METHODS: a hospital-based retrospective review of the records of premature infants screened for ROP between January 2010 and December 2015. Records of all premature infants screened for ROP in the neonatal unit and outpatient eye clinic were extracted. Information on Birth weights, Gestational age, Maternal risk factors (mode of delivery, pre-eclampsia/eclampsia) and Neonatal risk factors (neonatal sepsis, days on oxygen, blood transfusion) was recorded in a questionnaire then analysed. RESULTS: 103 infants were included in the study. Mean gestational age was 29.9 , 2.2 weeks and the mean birth weight was 1280.1 , 333.0 grams. Forty-three infants were diagnosed with ROP, a prevalence of 41.7%. Majority of these had Stage 1 or 2 ROP in Zone II, which spontaneously regressed with follow up. Nine infants were diagnosed with vision-threatening ROP (any Zone I disease or Stage 2/3 disease in Zone II with plus disease), a prevalence of 20.9%. All of these underwent laser treatment in the neonatal unit. The most significant risk factor was low gestational age. Other risk factors identified were: low birth weight and blood transfusions. CONCLUSION: ROP prevalence in sub-saharan Africa will match those in middle-income and high income countries in neonatal units with advanced care and low mortality. https://www.panafrican-med-journal.com/content/article/29/152/pdf/152.pdf retinaretinopathychild eye healthprematurityneonatal healthprematureretinopathy of prematurity |
| spellingShingle | Oscar Onyango Sarah Sitati Lucia Amolo Florence Murila Susan Wariua Gacheri Nyamu Moses Lango Atul Patel Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care The Pan African Medical Journal retina retinopathy child eye health prematurity neonatal health premature retinopathy of prematurity |
| title | Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care |
| title_full | Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care |
| title_fullStr | Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care |
| title_full_unstemmed | Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care |
| title_short | Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care |
| title_sort | retinopathy of prematurity in kenya prevalence and risk factors in a hospital with advanced neonatal care |
| topic | retina retinopathy child eye health prematurity neonatal health premature retinopathy of prematurity |
| url |
https://www.panafrican-med-journal.com/content/article/29/152/pdf/152.pdf
|
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