Timing of Surgery and Social Determinants of Health Related to Pathologic Complete Response after Total Neoadjuvant Therapy for Rectal Adenocarcinoma: Retrospective Study of National Cancer Database

Timing of Surgery and Social Determinants of Health Related to Pathologic Complete Response after Total Neoadjuvant Therapy for Rectal Adenocarcinoma: Retrospective Study of National Cancer Database

Total neoadjuvant therapy (TNT) for rectal adenocarcinoma (RAC) involves multi-agent chemotherapy and radiation before definitive surgery. Previous studies of the rest period (time between radiation and surgery) and pathologic complete response (pCR) have produced mixed results. The objective of thi...

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Bibliographic Details
Main Authors: Megan Mai, Jodi Goldman, Duke Appiah, Ramzi Abdulrahman, John Kidwell, Zheng Shi
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Current Oncology
Subjects:
rectal cancer
total neoadjuvant therapy
pathologic complete response
Online Access:https://www.mdpi.com/1718-7729/31/3/97

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