Comprehensive Evaluation of Different TiO<sub>2</sub>-Based Phosphopeptide Enrichment and Fractionation Methods for Phosphoproteomics

Comprehensive Evaluation of Different TiO<sub>2</sub>-Based Phosphopeptide Enrichment and Fractionation Methods for Phosphoproteomics

Protein phosphorylation is an essential post-translational modification that regulates multiple cellular processes. Due to their low stoichiometry and ionization efficiency, it is critical to efficiently enrich phosphopeptides for phosphoproteomics. Several phosphopeptide enrichment methods have bee...

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Bibliographic Details
Main Authors: Jiaran Li, Jifeng Wang, Yumeng Yan, Na Li, Xiaoqing Qing, Ailikemu Tuerxun, Xiaojing Guo, Xiulan Chen, Fuquan Yang
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
phosphoproteomics
TiO<sub>2</sub>
phosphopeptide enrichment
phosphopeptide fractionation
non-phosphopeptide excluder
deamidation
Online Access:https://www.mdpi.com/2073-4409/11/13/2047

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