Experimental study comparing burn healing effects of raw South African Shea butter and the samples from a Libyan market
Background: The fat extracted from the nut of the African Shea tree (Vitellaria paradoxa) is called Shea butter. It has multiple uses at the local level as it is used in cosmetic products and as a cocoa butter substitute in chocolate industries. It has a high nutritious value and is also a valuable...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Tripoli University
2020-11-01
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| Series: | Open Veterinary Journal |
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| Online Access: | https://www.openveterinaryjournal.com/OVJ-2019-12-369%20S.A.%20Treesh%20et%20al.pdf |
| _version_ | 1818778861471531008 |
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| author | Soad A. Treesh Sakina S. Saadawi Khairi A. Alennabi Suhera M. Aburawi Kholoud Lotfi Amal S. Ben Musa |
| author_facet | Soad A. Treesh Sakina S. Saadawi Khairi A. Alennabi Suhera M. Aburawi Kholoud Lotfi Amal S. Ben Musa |
| author_sort | Soad A. Treesh |
| collection | DOAJ |
| description | Background: The fat extracted from the nut of the African Shea tree (Vitellaria paradoxa) is called Shea butter. It has multiple uses at the local level as it is used in cosmetic products and as a cocoa butter substitute in chocolate industries. It has a high nutritious value and is also a valuable product on the local, national, and international markets, making it the ideal candidate to research and invest in.
Aim: This study is a comparative experimental study of the possible burn healing effects between imported South African raw Shea butter and samples in a Libyan market.
Method: The control samples were brought from South Africa (Benin traditional markets). A total of 18 different samples were collected from different sale centers in Tripoli, including pharmacies, beauty shops, and spices shops, in addition to one sample brought from Poland. Animal experiment on burn healing effect was carried out on nine male Sprague Dawley (350–400 g) rats aged 6–8 weeks old. After shaving the animal’s dorsum hair, a metal cube was used to create a deep second degree burn wound, and the cube was heated to 100°C for 20 seconds. Medication with Shea butter (control, T1, and T2) was initiated daily for one for these groups by the application of a thin film of the Shea butter samples on the burned areas. On days 1, 3, and 7, the rats were anesthetised and a sample from the burned scar tissue and skin adjacent were evaluated using pathological parameters.
Results: The histological study indicates that the use of Shea butter T1 as topical treatment induces an immune response, which enhances the form of the presence of a large number of inflammatory cells in the epidermis and dermis layers. The treatment of burned skin with T2 lasted for 72 hours and it showed slightly significant healing in the normal structure of proliferative granulation tissue with accumulation of fibroblasts and inflammatory cells surrounding the sebaceous glands and hair follicles. Small areas of the epidermis which formed few layers were observed and some hair roots were grown. This was well seen in cases of T1 and T2. Shea butter bought as raw might have a bad effect on burned skin.
Conclusion: Shea butter bought as raw might have bad effect on burned skin. On the other hand, the sample from Poland had a therapeutic effect, which was because of the additives such as avocado oil, grape seed oil, and others. |
| first_indexed | 2024-12-18T11:51:27Z |
| format | Article |
| id | doaj.art-0e8f9d383b1742d5a852122a6017589a |
| institution | Directory Open Access Journal |
| issn | 2218-6050 2218-6050 |
| language | English |
| last_indexed | 2024-12-18T11:51:27Z |
| publishDate | 2020-11-01 |
| publisher | Tripoli University |
| record_format | Article |
| series | Open Veterinary Journal |
| spelling | doaj.art-0e8f9d383b1742d5a852122a6017589a2022-12-21T21:09:09ZengTripoli UniversityOpen Veterinary Journal2218-60502218-60502020-11-01104431437http://dx.doi.org/10.4314/ovj.v10i4.10Experimental study comparing burn healing effects of raw South African Shea butter and the samples from a Libyan marketSoad A. Treesh0Sakina S. Saadawi1Khairi A. Alennabi2Suhera M. Aburawi3Kholoud Lotfi4Amal S. Ben Musa5Department of Histology and Medical Genetics, Faculty of Medicine, University of Tripoli, Tripoli, LibyaDepartment of Pharmacognosy, Faculty of Pharmacy, University of Tripoli, Tripoli, LibyaDepartment of Environment, Food and Biological Applications, Biotechnology Research Centre, Tripoli, LibyaDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, University of Tripoli, Tripoli, LibyaDepartment of Pharmacognosy, Faculty of Pharmacy, University of Tripoli, Tripoli, LibyaDepartment of Histology and Medical Genetics, Faculty of Medicine, University of Tripoli, Tripoli, LibyaBackground: The fat extracted from the nut of the African Shea tree (Vitellaria paradoxa) is called Shea butter. It has multiple uses at the local level as it is used in cosmetic products and as a cocoa butter substitute in chocolate industries. It has a high nutritious value and is also a valuable product on the local, national, and international markets, making it the ideal candidate to research and invest in. Aim: This study is a comparative experimental study of the possible burn healing effects between imported South African raw Shea butter and samples in a Libyan market. Method: The control samples were brought from South Africa (Benin traditional markets). A total of 18 different samples were collected from different sale centers in Tripoli, including pharmacies, beauty shops, and spices shops, in addition to one sample brought from Poland. Animal experiment on burn healing effect was carried out on nine male Sprague Dawley (350–400 g) rats aged 6–8 weeks old. After shaving the animal’s dorsum hair, a metal cube was used to create a deep second degree burn wound, and the cube was heated to 100°C for 20 seconds. Medication with Shea butter (control, T1, and T2) was initiated daily for one for these groups by the application of a thin film of the Shea butter samples on the burned areas. On days 1, 3, and 7, the rats were anesthetised and a sample from the burned scar tissue and skin adjacent were evaluated using pathological parameters. Results: The histological study indicates that the use of Shea butter T1 as topical treatment induces an immune response, which enhances the form of the presence of a large number of inflammatory cells in the epidermis and dermis layers. The treatment of burned skin with T2 lasted for 72 hours and it showed slightly significant healing in the normal structure of proliferative granulation tissue with accumulation of fibroblasts and inflammatory cells surrounding the sebaceous glands and hair follicles. Small areas of the epidermis which formed few layers were observed and some hair roots were grown. This was well seen in cases of T1 and T2. Shea butter bought as raw might have a bad effect on burned skin. Conclusion: Shea butter bought as raw might have bad effect on burned skin. On the other hand, the sample from Poland had a therapeutic effect, which was because of the additives such as avocado oil, grape seed oil, and others.https://www.openveterinaryjournal.com/OVJ-2019-12-369%20S.A.%20Treesh%20et%20al.pdfburnt skinhistopathologyshea butter |
| spellingShingle | Soad A. Treesh Sakina S. Saadawi Khairi A. Alennabi Suhera M. Aburawi Kholoud Lotfi Amal S. Ben Musa Experimental study comparing burn healing effects of raw South African Shea butter and the samples from a Libyan market Open Veterinary Journal burnt skin histopathology shea butter |
| title | Experimental study comparing burn healing effects of raw South African Shea butter and the samples from a Libyan market |
| title_full | Experimental study comparing burn healing effects of raw South African Shea butter and the samples from a Libyan market |
| title_fullStr | Experimental study comparing burn healing effects of raw South African Shea butter and the samples from a Libyan market |
| title_full_unstemmed | Experimental study comparing burn healing effects of raw South African Shea butter and the samples from a Libyan market |
| title_short | Experimental study comparing burn healing effects of raw South African Shea butter and the samples from a Libyan market |
| title_sort | experimental study comparing burn healing effects of raw south african shea butter and the samples from a libyan market |
| topic | burnt skin histopathology shea butter |
| url | https://www.openveterinaryjournal.com/OVJ-2019-12-369%20S.A.%20Treesh%20et%20al.pdf |
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