The epidemiology and etiology of onychomycosis in 2 laboratory centers affiliated to Tehran university of medical sciences during 2019-2020
Background and Objectives: Onychomycosis is caused by dermatophyte species, non- dermatophyte moulds (NDMs), and accounts for roughly 50% of all nail diseases. As the prevalence of onychomycosis is increasing, new epidemiologic documents may help with treatment and prevention. The present investiga...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2022-04-01
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| Series: | Iranian Journal of Microbiology |
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| Online Access: | https://ijm.tums.ac.ir/index.php/ijm/article/view/3356 |
| _version_ | 1818239600105095168 |
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| author | Taraneh Razavyoon Seyed Jamal Hashemi Parvin Mansouri Zahra Rafat Ali Akbar Saboor-Yaraghi Hasti Kamali Sarvestani Zeinab Ghasemi |
| author_facet | Taraneh Razavyoon Seyed Jamal Hashemi Parvin Mansouri Zahra Rafat Ali Akbar Saboor-Yaraghi Hasti Kamali Sarvestani Zeinab Ghasemi |
| author_sort | Taraneh Razavyoon |
| collection | DOAJ |
| description |
Background and Objectives: Onychomycosis is caused by dermatophyte species, non- dermatophyte moulds (NDMs), and accounts for roughly 50% of all nail diseases. As the prevalence of onychomycosis is increasing, new epidemiologic documents may help with treatment and prevention. The present investigation aims to determine the epidemiological profile of onychomycosis in 2 mycology laboratories.
Materials and Methods: A cross-sectional study conducted during eight months (2019-2020) on 169 patients with positive nail mycology tests referred to two mycological laboratory centers affiliated with Tehran University of Medical Science. The nail clippings were examined by direct smear and culture. Also, molecular assays were performed if needed.
Results: 10% of nail lesions referred to Razi Hospital (RH), and 30% of nail lesions referred to TUMS mycology laboratory were positive. Middle age (40-60) suffer more from onychomycosis. Aspergillus flavus, Trichophyton mentagrophytes, and Candida albicans were the most common etiologic agents in each of the three main classes of fungi causing onychomycosis. Females were more infected. NDMs were the predominant etiologic agents, and toenails were the most common site of onychomycosis.
Conclusion: The pattern of etiologic agents and clinical signs of onychomycosis differs according to geographical region and age, so repeated epidemiological surveys of onychomycosis seem to be fundamental.
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| first_indexed | 2024-12-12T13:00:07Z |
| format | Article |
| id | doaj.art-0e915920679e4cbdb882c370e893f5d2 |
| institution | Directory Open Access Journal |
| issn | 2008-3289 2008-4447 |
| language | English |
| last_indexed | 2024-12-12T13:00:07Z |
| publishDate | 2022-04-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Microbiology |
| spelling | doaj.art-0e915920679e4cbdb882c370e893f5d22022-12-22T00:23:48ZengTehran University of Medical SciencesIranian Journal of Microbiology2008-32892008-44472022-04-0114210.18502/ijm.v14i2.9196The epidemiology and etiology of onychomycosis in 2 laboratory centers affiliated to Tehran university of medical sciences during 2019-2020Taraneh Razavyoon0Seyed Jamal Hashemi1Parvin Mansouri2Zahra Rafat3Ali Akbar Saboor-Yaraghi4Hasti Kamali Sarvestani5Zeinab Ghasemi6Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranSkin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Parasitology and Mycology, School of Medicine, Guilan University of Medical Sciences, Rasht, IranDepartment of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Mycology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran Background and Objectives: Onychomycosis is caused by dermatophyte species, non- dermatophyte moulds (NDMs), and accounts for roughly 50% of all nail diseases. As the prevalence of onychomycosis is increasing, new epidemiologic documents may help with treatment and prevention. The present investigation aims to determine the epidemiological profile of onychomycosis in 2 mycology laboratories. Materials and Methods: A cross-sectional study conducted during eight months (2019-2020) on 169 patients with positive nail mycology tests referred to two mycological laboratory centers affiliated with Tehran University of Medical Science. The nail clippings were examined by direct smear and culture. Also, molecular assays were performed if needed. Results: 10% of nail lesions referred to Razi Hospital (RH), and 30% of nail lesions referred to TUMS mycology laboratory were positive. Middle age (40-60) suffer more from onychomycosis. Aspergillus flavus, Trichophyton mentagrophytes, and Candida albicans were the most common etiologic agents in each of the three main classes of fungi causing onychomycosis. Females were more infected. NDMs were the predominant etiologic agents, and toenails were the most common site of onychomycosis. Conclusion: The pattern of etiologic agents and clinical signs of onychomycosis differs according to geographical region and age, so repeated epidemiological surveys of onychomycosis seem to be fundamental. https://ijm.tums.ac.ir/index.php/ijm/article/view/3356Onychomycosis;Epidemiology;Dermatophyte;Saprophyte;Yeast |
| spellingShingle | Taraneh Razavyoon Seyed Jamal Hashemi Parvin Mansouri Zahra Rafat Ali Akbar Saboor-Yaraghi Hasti Kamali Sarvestani Zeinab Ghasemi The epidemiology and etiology of onychomycosis in 2 laboratory centers affiliated to Tehran university of medical sciences during 2019-2020 Iranian Journal of Microbiology Onychomycosis; Epidemiology; Dermatophyte; Saprophyte; Yeast |
| title | The epidemiology and etiology of onychomycosis in 2 laboratory centers affiliated to Tehran university of medical sciences during 2019-2020 |
| title_full | The epidemiology and etiology of onychomycosis in 2 laboratory centers affiliated to Tehran university of medical sciences during 2019-2020 |
| title_fullStr | The epidemiology and etiology of onychomycosis in 2 laboratory centers affiliated to Tehran university of medical sciences during 2019-2020 |
| title_full_unstemmed | The epidemiology and etiology of onychomycosis in 2 laboratory centers affiliated to Tehran university of medical sciences during 2019-2020 |
| title_short | The epidemiology and etiology of onychomycosis in 2 laboratory centers affiliated to Tehran university of medical sciences during 2019-2020 |
| title_sort | epidemiology and etiology of onychomycosis in 2 laboratory centers affiliated to tehran university of medical sciences during 2019 2020 |
| topic | Onychomycosis; Epidemiology; Dermatophyte; Saprophyte; Yeast |
| url | https://ijm.tums.ac.ir/index.php/ijm/article/view/3356 |
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