A neuron-specific deletion of the microRNA-processing enzyme DICER induces severe but transient obesity in mice.
MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression post-transcriptionally. MiRNAs are implicated in various biological processes associated with obesity, including adipocyte differentiation and lipid metabolism. We used a neuronal-specific inhibition of miRNA matura...
Main Authors: | Géraldine M Mang, Sylvain Pradervand, Ngoc-Hien Du, Alaaddin Bulak Arpat, Frédéric Preitner, Leonore Wigger, David Gatfield, Paul Franken |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4309537?pdf=render |
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