Incorporation of albumin fusion proteins into fibrin clots <it>in vitro </it>and <it>in vivo</it>: comparison of different fusion motifs recognized by factor XIIIa

Incorporation of albumin fusion proteins into fibrin clots <it>in vitro </it>and <it>in vivo</it>: comparison of different fusion motifs recognized by factor XIIIa

<p>Abstract</p> <p>Background</p> <p>The transglutaminase activated factor XIII (FXIIIa) acts to strengthen pathological fibrin clots and to slow their dissolution, in part by crosslinking active α<sub>2</sub>-antiplasmin (α<sub>2</sub>AP) to fib...

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Bibliographic Details
Main Authors: Sheffield William P, Eltringham-Smith Louise J
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/11/127

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