Characteristics of Hantaviruses as Causative Agents of the Zoonotic Hemorrhagic Fevers
Hemorrhagic fever with renal syndrome (HFRS) has been a major concern for public health in different countries of the Euroasian continent for decades. In 1970s the disease was associated with newly discovered viruses that were to become new members (under the genus Hantavirus) of the family Bunyavir...
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| Format: | Article |
| Language: | Russian |
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Numikom LLC
2017-06-01
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| Series: | Эпидемиология и вакцинопрофилактика |
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| Online Access: | https://www.epidemvac.ru/jour/article/view/273 |
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| author | A. A. Ishmukhametov T. K. Dzagurova V. G. Morozov C. C. Kurashova M. V. Balovneva C. E. Sotskova E. A. Tkachenko |
| author_facet | A. A. Ishmukhametov T. K. Dzagurova V. G. Morozov C. C. Kurashova M. V. Balovneva C. E. Sotskova E. A. Tkachenko |
| author_sort | A. A. Ishmukhametov |
| collection | DOAJ |
| description | Hemorrhagic fever with renal syndrome (HFRS) has been a major concern for public health in different countries of the Euroasian continent for decades. In 1970s the disease was associated with newly discovered viruses that were to become new members (under the genus Hantavirus) of the family Bunyaviridae. During a deadly outbreak of pulmonary syndrome in the southwestern United States in 1993, it was shown that causative agents of this devastating disease (designated hantavirus cardio-pulmonary syndrome, HCPS) were also hantaviruses. By now hantaviruses are found worldwide and associated with different species of the order Rodentia , which are their natural carriers. Hantaviruses persistently infect rodents, however do not cause any disease in them and are transmitted to humans through aerosolized excreta. For a long time studies of hantaviruses were limited by their high pathogenicity, absence of animal model of infection, and poor growth in cell cultures. With the rapid development of molecular biological techniques in last several years substantial progress has been made in various fields of hantavirus research. Different aspects of hantavirus ecology, molecular biology, morphology and pathogenesis, as well as current diagnostic methods and other characteristics of hantaviruses are considered in this review. |
| first_indexed | 2024-04-10T02:50:38Z |
| format | Article |
| id | doaj.art-0e957cdd48e6412ab301ba79a844723d |
| institution | Directory Open Access Journal |
| issn | 2073-3046 2619-0494 |
| language | Russian |
| last_indexed | 2025-03-14T11:08:42Z |
| publishDate | 2017-06-01 |
| publisher | Numikom LLC |
| record_format | Article |
| series | Эпидемиология и вакцинопрофилактика |
| spelling | doaj.art-0e957cdd48e6412ab301ba79a844723d2025-03-02T10:40:28ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942017-06-01163263210.31631/2073-3046-2017-16-3-26-32272Characteristics of Hantaviruses as Causative Agents of the Zoonotic Hemorrhagic FeversA. A. Ishmukhametov0T. K. Dzagurova1V. G. MorozovC. C. Kurashova2M. V. Balovneva3C. E. Sotskova4E. A. Tkachenko5Federal State Budget Institution of Science «Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences»; Federal State Autonomous Educational Institution of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Healthcare of the Russian Federation; LLC «Hepatolog»Federal State Budget Institution of Science «Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences»Federal State Budget Institution of Science «Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences»Federal State Budget Institution of Science «Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences»Federal State Budget Institution of Science «Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences»Federal State Budget Institution of Science «Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences»; Federal State Autonomous Educational Institution of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Healthcare of the Russian Federation; LLC «Hepatolog»Hemorrhagic fever with renal syndrome (HFRS) has been a major concern for public health in different countries of the Euroasian continent for decades. In 1970s the disease was associated with newly discovered viruses that were to become new members (under the genus Hantavirus) of the family Bunyaviridae. During a deadly outbreak of pulmonary syndrome in the southwestern United States in 1993, it was shown that causative agents of this devastating disease (designated hantavirus cardio-pulmonary syndrome, HCPS) were also hantaviruses. By now hantaviruses are found worldwide and associated with different species of the order Rodentia , which are their natural carriers. Hantaviruses persistently infect rodents, however do not cause any disease in them and are transmitted to humans through aerosolized excreta. For a long time studies of hantaviruses were limited by their high pathogenicity, absence of animal model of infection, and poor growth in cell cultures. With the rapid development of molecular biological techniques in last several years substantial progress has been made in various fields of hantavirus research. Different aspects of hantavirus ecology, molecular biology, morphology and pathogenesis, as well as current diagnostic methods and other characteristics of hantaviruses are considered in this review.https://www.epidemvac.ru/jour/article/view/273хантавирусглпсхпсhantavirushfrshps |
| spellingShingle | A. A. Ishmukhametov T. K. Dzagurova V. G. Morozov C. C. Kurashova M. V. Balovneva C. E. Sotskova E. A. Tkachenko Characteristics of Hantaviruses as Causative Agents of the Zoonotic Hemorrhagic Fevers Эпидемиология и вакцинопрофилактика хантавирус глпс хпс hantavirus hfrs hps |
| title | Characteristics of Hantaviruses as Causative Agents of the Zoonotic Hemorrhagic Fevers |
| title_full | Characteristics of Hantaviruses as Causative Agents of the Zoonotic Hemorrhagic Fevers |
| title_fullStr | Characteristics of Hantaviruses as Causative Agents of the Zoonotic Hemorrhagic Fevers |
| title_full_unstemmed | Characteristics of Hantaviruses as Causative Agents of the Zoonotic Hemorrhagic Fevers |
| title_short | Characteristics of Hantaviruses as Causative Agents of the Zoonotic Hemorrhagic Fevers |
| title_sort | characteristics of hantaviruses as causative agents of the zoonotic hemorrhagic fevers |
| topic | хантавирус глпс хпс hantavirus hfrs hps |
| url | https://www.epidemvac.ru/jour/article/view/273 |
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