Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report

<p>Abstract</p> <p>Introduction</p> <p>Bevacizumab is a monoclonal antibody against vascular endothelial growth factor. It is widely used in the treatment of metastatic colorectal cancer. It has some specific side effects including severe bleeding, wound healing problem...

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Main Authors: Uysal Mukremin, Goksu Sema, Coskun Hasan, Savas Burhan, Ozdogan Mustafa, Bozcuk Hakan
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Journal of Medical Case Reports
Subjects:
Online Access:http://www.jmedicalcasereports.com/content/6/1/188
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author Uysal Mukremin
Goksu Sema
Coskun Hasan
Savas Burhan
Ozdogan Mustafa
Bozcuk Hakan
author_facet Uysal Mukremin
Goksu Sema
Coskun Hasan
Savas Burhan
Ozdogan Mustafa
Bozcuk Hakan
author_sort Uysal Mukremin
collection DOAJ
description <p>Abstract</p> <p>Introduction</p> <p>Bevacizumab is a monoclonal antibody against vascular endothelial growth factor. It is widely used in the treatment of metastatic colorectal cancer. It has some specific side effects including severe bleeding, wound healing problems, gastrointestinal perforation, proteinuria and hypertension.</p> <p>Case presentation</p> <p>We present the case of a 65-year old Asian man with synovial metastasis of the knee who experienced intraarticular hemorrhage after bevacizumab treatment. He presented with monoarthritis of the left knee.</p> <p>Conclusion</p> <p>Bevacizumab-related hemorrhage can cause serious morbidity and unusual sites of hemorrhage may be seen.</p>
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spelling doaj.art-0e95df47671e44bf96ce9a3d4fc6e5822022-12-22T02:50:15ZengBMCJournal of Medical Case Reports1752-19472012-07-016118810.1186/1752-1947-6-188Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case reportUysal MukreminGoksu SemaCoskun HasanSavas BurhanOzdogan MustafaBozcuk Hakan<p>Abstract</p> <p>Introduction</p> <p>Bevacizumab is a monoclonal antibody against vascular endothelial growth factor. It is widely used in the treatment of metastatic colorectal cancer. It has some specific side effects including severe bleeding, wound healing problems, gastrointestinal perforation, proteinuria and hypertension.</p> <p>Case presentation</p> <p>We present the case of a 65-year old Asian man with synovial metastasis of the knee who experienced intraarticular hemorrhage after bevacizumab treatment. He presented with monoarthritis of the left knee.</p> <p>Conclusion</p> <p>Bevacizumab-related hemorrhage can cause serious morbidity and unusual sites of hemorrhage may be seen.</p>http://www.jmedicalcasereports.com/content/6/1/188BevacizumabColorectal cancerSynovial metastasisIntaarticular hemorrhage
spellingShingle Uysal Mukremin
Goksu Sema
Coskun Hasan
Savas Burhan
Ozdogan Mustafa
Bozcuk Hakan
Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report
Journal of Medical Case Reports
Bevacizumab
Colorectal cancer
Synovial metastasis
Intaarticular hemorrhage
title Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report
title_full Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report
title_fullStr Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report
title_full_unstemmed Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report
title_short Intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer: a case report
title_sort intraarticular hemorrhage due to bevacizumab in a patient with metastatic colorectal cancer a case report
topic Bevacizumab
Colorectal cancer
Synovial metastasis
Intaarticular hemorrhage
url http://www.jmedicalcasereports.com/content/6/1/188
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AT goksusema intraarticularhemorrhageduetobevacizumabinapatientwithmetastaticcolorectalcanceracasereport
AT coskunhasan intraarticularhemorrhageduetobevacizumabinapatientwithmetastaticcolorectalcanceracasereport
AT savasburhan intraarticularhemorrhageduetobevacizumabinapatientwithmetastaticcolorectalcanceracasereport
AT ozdoganmustafa intraarticularhemorrhageduetobevacizumabinapatientwithmetastaticcolorectalcanceracasereport
AT bozcukhakan intraarticularhemorrhageduetobevacizumabinapatientwithmetastaticcolorectalcanceracasereport