LDH ACTIVITY IN COPPER INTOXICATION OF CARASSIUS AURATUS GIBELIO GILLS AND INTESTINE

The pathological effects of two sublethal concentrations (100 µg/l and 250 µg/l) of copper (CuSO4x5H2O) on goldfish Carassius auratus gibelio were studied for 7,14 and 21 days. The specific activity of LDH in gills and intestine, two target organs that uptake the metal from the water were assayed. I...

Full description

Bibliographic Details
Main Authors: DANIELA TEODORESCU, MARIA CRISTINA MUNTEANU, ANDREEA CRISTINA STAICU, LOTUS MESTER, ANCA DINISCHIOTU
Format: Article
Language:English
Published: Agroprint Timisoara 2023-11-01
Series:Scientific Papers Animal Science and Biotechnologies
Subjects:
Online Access:https://spasb.ro/index.php/public_html/article/view/2039
_version_ 1797223771067645952
author DANIELA TEODORESCU
MARIA CRISTINA MUNTEANU
ANDREEA CRISTINA STAICU
LOTUS MESTER
ANCA DINISCHIOTU
author_facet DANIELA TEODORESCU
MARIA CRISTINA MUNTEANU
ANDREEA CRISTINA STAICU
LOTUS MESTER
ANCA DINISCHIOTU
author_sort DANIELA TEODORESCU
collection DOAJ
description The pathological effects of two sublethal concentrations (100 µg/l and 250 µg/l) of copper (CuSO4x5H2O) on goldfish Carassius auratus gibelio were studied for 7,14 and 21 days. The specific activity of LDH in gills and intestine, two target organs that uptake the metal from the water were assayed. In gills at 100 µg Cu2+/l the specific activity of LDH was gradually decreasing, while in the intestine, after 7 days of exposure, the enzymatic activity was distinct significantly increased. LDH activity demonstrated a hypoxic condition and a stimulation of glycolysis. In the both organs ,the 250 µg Cu2+/l concentration generated a decrease of LDH specific activity after 7 days followed by an increase of this after 14 and 21 days of exposure. Histologically, the modifications are, generally, directly correlated with the toxicant dose and exposure time.
first_indexed 2024-04-24T13:42:31Z
format Article
id doaj.art-0ea123dd70b64f929fed3220bb12be6a
institution Directory Open Access Journal
issn 1841-9364
2344-4576
language English
last_indexed 2024-04-24T13:42:31Z
publishDate 2023-11-01
publisher Agroprint Timisoara
record_format Article
series Scientific Papers Animal Science and Biotechnologies
spelling doaj.art-0ea123dd70b64f929fed3220bb12be6a2024-04-04T07:37:04ZengAgroprint TimisoaraScientific Papers Animal Science and Biotechnologies1841-93642344-45762023-11-014121691692039LDH ACTIVITY IN COPPER INTOXICATION OF CARASSIUS AURATUS GIBELIO GILLS AND INTESTINEDANIELA TEODORESCU0MARIA CRISTINA MUNTEANU1ANDREEA CRISTINA STAICU2LOTUS MESTER3ANCA DINISCHIOTU4University of Bucharest, Faculty of Biology, Bucharest University of Bucharest, Faculty of Biology, Bucharest University of Bucharest, Faculty of Biology, Bucharest University of Bucharest, Faculty of Biology, Bucharest University of Bucharest, Faculty of Biology, Bucharest The pathological effects of two sublethal concentrations (100 µg/l and 250 µg/l) of copper (CuSO4x5H2O) on goldfish Carassius auratus gibelio were studied for 7,14 and 21 days. The specific activity of LDH in gills and intestine, two target organs that uptake the metal from the water were assayed. In gills at 100 µg Cu2+/l the specific activity of LDH was gradually decreasing, while in the intestine, after 7 days of exposure, the enzymatic activity was distinct significantly increased. LDH activity demonstrated a hypoxic condition and a stimulation of glycolysis. In the both organs ,the 250 µg Cu2+/l concentration generated a decrease of LDH specific activity after 7 days followed by an increase of this after 14 and 21 days of exposure. Histologically, the modifications are, generally, directly correlated with the toxicant dose and exposure time.https://spasb.ro/index.php/public_html/article/view/2039gold fishcopper toxicityldhhistopathology
spellingShingle DANIELA TEODORESCU
MARIA CRISTINA MUNTEANU
ANDREEA CRISTINA STAICU
LOTUS MESTER
ANCA DINISCHIOTU
LDH ACTIVITY IN COPPER INTOXICATION OF CARASSIUS AURATUS GIBELIO GILLS AND INTESTINE
Scientific Papers Animal Science and Biotechnologies
gold fish
copper toxicity
ldh
histopathology
title LDH ACTIVITY IN COPPER INTOXICATION OF CARASSIUS AURATUS GIBELIO GILLS AND INTESTINE
title_full LDH ACTIVITY IN COPPER INTOXICATION OF CARASSIUS AURATUS GIBELIO GILLS AND INTESTINE
title_fullStr LDH ACTIVITY IN COPPER INTOXICATION OF CARASSIUS AURATUS GIBELIO GILLS AND INTESTINE
title_full_unstemmed LDH ACTIVITY IN COPPER INTOXICATION OF CARASSIUS AURATUS GIBELIO GILLS AND INTESTINE
title_short LDH ACTIVITY IN COPPER INTOXICATION OF CARASSIUS AURATUS GIBELIO GILLS AND INTESTINE
title_sort ldh activity in copper intoxication of carassius auratus gibelio gills and intestine
topic gold fish
copper toxicity
ldh
histopathology
url https://spasb.ro/index.php/public_html/article/view/2039
work_keys_str_mv AT danielateodorescu ldhactivityincopperintoxicationofcarassiusauratusgibeliogillsandintestine
AT mariacristinamunteanu ldhactivityincopperintoxicationofcarassiusauratusgibeliogillsandintestine
AT andreeacristinastaicu ldhactivityincopperintoxicationofcarassiusauratusgibeliogillsandintestine
AT lotusmester ldhactivityincopperintoxicationofcarassiusauratusgibeliogillsandintestine
AT ancadinischiotu ldhactivityincopperintoxicationofcarassiusauratusgibeliogillsandintestine