Snaring Self-Expanding Devices to Facilitate Transcatheter Aortic Valve Replacement in Patients with Complex Aortic Anatomies

The snare-assisted technique has been described to facilitate transcatheter aortic valve replacement (TAVR) delivery system advancement in complex aortic anatomies. However, the evidence is limited to case reports. To evaluate the safety profile of the snare-facilitated approach and its impact on se...

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Main Authors: Yi-Jun Yao, Zhen-Gang Zhao, Xi Wang, Yong Peng, Jia-Fu Wei, Sen He, Yi-Jian Li, Jing-Jing He, Zhong-Kai Zhu, Yuan Feng, Mao Chen
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/12/15/5067
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author Yi-Jun Yao
Zhen-Gang Zhao
Xi Wang
Yong Peng
Jia-Fu Wei
Sen He
Yi-Jian Li
Jing-Jing He
Zhong-Kai Zhu
Yuan Feng
Mao Chen
author_facet Yi-Jun Yao
Zhen-Gang Zhao
Xi Wang
Yong Peng
Jia-Fu Wei
Sen He
Yi-Jian Li
Jing-Jing He
Zhong-Kai Zhu
Yuan Feng
Mao Chen
author_sort Yi-Jun Yao
collection DOAJ
description The snare-assisted technique has been described to facilitate transcatheter aortic valve replacement (TAVR) delivery system advancement in complex aortic anatomies. However, the evidence is limited to case reports. To evaluate the safety profile of the snare-facilitated approach and its impact on self-expanding (SE) TAVR outcomes, we collected consecutive patients who underwent transfemoral SE-TAVR for aortic stenosis, using propensity score matching (PSM) separately in tricuspid and type-0 and type-1 bicuspid aortic valve morphology between the snare and non-snare groups. In 766 patients, despite the snare group having significantly larger annulus angulation and maximal ascending aortic diameter, both groups achieved comparable 30-day device success rates, regardless of first-generation or new-generation valve use. After PSM, the snare group had a significantly lower new permanent pacemaker implantation rate among 193 type-0 patients (3.3% vs. 18.3%, <i>p</i> = 0.01). The ipsilateral group used new-generation valves less frequently (23.0% vs. 75.4%, <i>p</i> < 0.001), but there were no significant inter-group differences in procedure-related events, except for a lower incidence of PVL ≥ mild in the ipsilateral group (14.9% vs. 32.3%, <i>p</i> = 0.01). In conclusion, the snare-assisted technique appears useful in SE-TAVR with angulated aortic root anatomy, and the benefits were comparable between ipsilateral and contralateral snare techniques.
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spelling doaj.art-0ea2de1d61e94f6a9a2c11108e76aee02023-11-18T23:08:57ZengMDPI AGJournal of Clinical Medicine2077-03832023-08-011215506710.3390/jcm12155067Snaring Self-Expanding Devices to Facilitate Transcatheter Aortic Valve Replacement in Patients with Complex Aortic AnatomiesYi-Jun Yao0Zhen-Gang Zhao1Xi Wang2Yong Peng3Jia-Fu Wei4Sen He5Yi-Jian Li6Jing-Jing He7Zhong-Kai Zhu8Yuan Feng9Mao Chen10Department of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, ChinaThe snare-assisted technique has been described to facilitate transcatheter aortic valve replacement (TAVR) delivery system advancement in complex aortic anatomies. However, the evidence is limited to case reports. To evaluate the safety profile of the snare-facilitated approach and its impact on self-expanding (SE) TAVR outcomes, we collected consecutive patients who underwent transfemoral SE-TAVR for aortic stenosis, using propensity score matching (PSM) separately in tricuspid and type-0 and type-1 bicuspid aortic valve morphology between the snare and non-snare groups. In 766 patients, despite the snare group having significantly larger annulus angulation and maximal ascending aortic diameter, both groups achieved comparable 30-day device success rates, regardless of first-generation or new-generation valve use. After PSM, the snare group had a significantly lower new permanent pacemaker implantation rate among 193 type-0 patients (3.3% vs. 18.3%, <i>p</i> = 0.01). The ipsilateral group used new-generation valves less frequently (23.0% vs. 75.4%, <i>p</i> < 0.001), but there were no significant inter-group differences in procedure-related events, except for a lower incidence of PVL ≥ mild in the ipsilateral group (14.9% vs. 32.3%, <i>p</i> = 0.01). In conclusion, the snare-assisted technique appears useful in SE-TAVR with angulated aortic root anatomy, and the benefits were comparable between ipsilateral and contralateral snare techniques.https://www.mdpi.com/2077-0383/12/15/5067transcatheter aortic valve replacementaortic stenosissnareannulus angulationbicuspid aortic valve
spellingShingle Yi-Jun Yao
Zhen-Gang Zhao
Xi Wang
Yong Peng
Jia-Fu Wei
Sen He
Yi-Jian Li
Jing-Jing He
Zhong-Kai Zhu
Yuan Feng
Mao Chen
Snaring Self-Expanding Devices to Facilitate Transcatheter Aortic Valve Replacement in Patients with Complex Aortic Anatomies
Journal of Clinical Medicine
transcatheter aortic valve replacement
aortic stenosis
snare
annulus angulation
bicuspid aortic valve
title Snaring Self-Expanding Devices to Facilitate Transcatheter Aortic Valve Replacement in Patients with Complex Aortic Anatomies
title_full Snaring Self-Expanding Devices to Facilitate Transcatheter Aortic Valve Replacement in Patients with Complex Aortic Anatomies
title_fullStr Snaring Self-Expanding Devices to Facilitate Transcatheter Aortic Valve Replacement in Patients with Complex Aortic Anatomies
title_full_unstemmed Snaring Self-Expanding Devices to Facilitate Transcatheter Aortic Valve Replacement in Patients with Complex Aortic Anatomies
title_short Snaring Self-Expanding Devices to Facilitate Transcatheter Aortic Valve Replacement in Patients with Complex Aortic Anatomies
title_sort snaring self expanding devices to facilitate transcatheter aortic valve replacement in patients with complex aortic anatomies
topic transcatheter aortic valve replacement
aortic stenosis
snare
annulus angulation
bicuspid aortic valve
url https://www.mdpi.com/2077-0383/12/15/5067
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