A review of cardio-pulmonary microvascular dysfunction in pulmonary hypertension
Microvascular dysfunction progressing to pulmonary hypertension can be a primary cause of right ventricular failure or a secondary cause because of an underlying systemic illness. Little is known regarding the etiology and epidemiology of coronary microvascular dysfunction in pulmonary hypertension....
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-02-01
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| Series: | American Heart Journal Plus |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666602223000071 |
| _version_ | 1828035771194408960 |
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| author | Cyrus Vahdatpour Samuel Epstein Kirk Jones Madeline Smoot Alex Parker John Ryan Andrew Bryant |
| author_facet | Cyrus Vahdatpour Samuel Epstein Kirk Jones Madeline Smoot Alex Parker John Ryan Andrew Bryant |
| author_sort | Cyrus Vahdatpour |
| collection | DOAJ |
| description | Microvascular dysfunction progressing to pulmonary hypertension can be a primary cause of right ventricular failure or a secondary cause because of an underlying systemic illness. Little is known regarding the etiology and epidemiology of coronary microvascular dysfunction in pulmonary hypertension. Despite this limitation, its presence has been described in patients with pulmonary hypertension. This review focuses on the pathogenesis of cardiac and pulmonary microvascular dysfunction in pulmonary hypertension. Additionally, this review provides a contemporary assessment on the diagnosis and treatment of microvascular dysfunction in patients in pulmonary hypertension. This topic is important to raise awareness of microvascular dysfunction in the coronary and pulmonary circulation, so that future studies will investigate its impact on the pulmonary hypertension patient cohort. |
| first_indexed | 2024-04-10T15:51:21Z |
| format | Article |
| id | doaj.art-0ea30e00ecb5440a8681b1c9d64cbd35 |
| institution | Directory Open Access Journal |
| issn | 2666-6022 |
| language | English |
| last_indexed | 2024-04-10T15:51:21Z |
| publishDate | 2023-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Heart Journal Plus |
| spelling | doaj.art-0ea30e00ecb5440a8681b1c9d64cbd352023-02-11T04:16:32ZengElsevierAmerican Heart Journal Plus2666-60222023-02-0126100255A review of cardio-pulmonary microvascular dysfunction in pulmonary hypertensionCyrus Vahdatpour0Samuel Epstein1Kirk Jones2Madeline Smoot3Alex Parker4John Ryan5Andrew Bryant6Department of Pulmonary Critical Care and Sleep Medicine, University of Florida, Gainesville, FL, USA; Corresponding author at: Department of Pulmonary, Critical Care, and Sleep Medicine, University of Florida, P.O. Box 100225 JHMHC, Gainesville, FL 32610-0225, USA.Department of Medicine, University of Florida, Gainesville, FL, USADepartment of Medicine, University of Florida, Gainesville, FL, USADepartment of Medicine, University of Florida, Gainesville, FL, USADepartment of Cardiology, University of Florida, Gainesville, FL, USADepartment of Cardiovascular Medicine, University of Utah, Salt Lake City, UT, USADepartment of Pulmonary Critical Care and Sleep Medicine, University of Florida, Gainesville, FL, USAMicrovascular dysfunction progressing to pulmonary hypertension can be a primary cause of right ventricular failure or a secondary cause because of an underlying systemic illness. Little is known regarding the etiology and epidemiology of coronary microvascular dysfunction in pulmonary hypertension. Despite this limitation, its presence has been described in patients with pulmonary hypertension. This review focuses on the pathogenesis of cardiac and pulmonary microvascular dysfunction in pulmonary hypertension. Additionally, this review provides a contemporary assessment on the diagnosis and treatment of microvascular dysfunction in patients in pulmonary hypertension. This topic is important to raise awareness of microvascular dysfunction in the coronary and pulmonary circulation, so that future studies will investigate its impact on the pulmonary hypertension patient cohort.http://www.sciencedirect.com/science/article/pii/S2666602223000071Microvascular dysfunctionPulmonary hypertensionRight heart failure |
| spellingShingle | Cyrus Vahdatpour Samuel Epstein Kirk Jones Madeline Smoot Alex Parker John Ryan Andrew Bryant A review of cardio-pulmonary microvascular dysfunction in pulmonary hypertension American Heart Journal Plus Microvascular dysfunction Pulmonary hypertension Right heart failure |
| title | A review of cardio-pulmonary microvascular dysfunction in pulmonary hypertension |
| title_full | A review of cardio-pulmonary microvascular dysfunction in pulmonary hypertension |
| title_fullStr | A review of cardio-pulmonary microvascular dysfunction in pulmonary hypertension |
| title_full_unstemmed | A review of cardio-pulmonary microvascular dysfunction in pulmonary hypertension |
| title_short | A review of cardio-pulmonary microvascular dysfunction in pulmonary hypertension |
| title_sort | review of cardio pulmonary microvascular dysfunction in pulmonary hypertension |
| topic | Microvascular dysfunction Pulmonary hypertension Right heart failure |
| url | http://www.sciencedirect.com/science/article/pii/S2666602223000071 |
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