Phosphatase and Tensin Homolog in Non-neoplastic Digestive Disease: More Than Just Tumor Suppressor

Phosphatase and Tensin Homolog in Non-neoplastic Digestive Disease: More Than Just Tumor Suppressor

The Phosphatase and tensin homolog (PTEN) gene is one of the most important tumor suppressor genes, which acts through its unique protein phosphatase and lipid phosphatase activity. PTEN protein is widely distributed and exhibits complex biological functions and regulatory modes. It is involved in t...

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Bibliographic Details
Main Authors: Tianyu He, Xiaoyun Zhang, Jianyu Hao, Shigang Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Physiology
Subjects:
PTEN
tumor suppressor
PI3K/AKT pathway
digestive organs
infection
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.684529/full

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