Ovarian Cancer-Associated Mesothelial Cells: Transdifferentiation to Minions of Cancer and Orchestrate Developing Peritoneal Dissemination

Ovarian Cancer-Associated Mesothelial Cells: Transdifferentiation to Minions of Cancer and Orchestrate Developing Peritoneal Dissemination

Ovarian cancer has one of the poorest prognoses among carcinomas. Advanced ovarian cancer often develops ascites and peritoneal dissemination, which is one of the poor prognostic factors. From the perspective of the “seed and soil” hypothesis, the intra-abdominal environment is like the soil for the...

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Bibliographic Details
Main Authors: Kazumasa Mogi, Masato Yoshihara, Shohei Iyoshi, Kazuhisa Kitami, Kaname Uno, Sho Tano, Yoshihiro Koya, Mai Sugiyama, Yoshihiko Yamakita, Akihiro Nawa, Hiroyuki Tomita, Hiroaki Kajiyama
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
ovarian cancer
peritoneal dissemination
mesothelial cells
epithelial mesenchymal transition
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/13/6/1352

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