Clinical features and visual outcomes of pediatric optic neuritis in the Indian population: A prospective study
Purpose: Optic neuritis, defined as inflammation of the optic nerve, is the most common optic neuropathy affecting adults. Various studies in Southeast Asia have shown that the clinical profile of optic neuritis might differ in these regions from that reported in the western literature. Through thi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=2;spage=637;epage=642;aulast=Kowsalya |
| _version_ | 1797775129486295040 |
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| author | Akkayasamy Kowsalya Uma Ramalingam Sameer Chaudhary Mahesh Kumar |
| author_facet | Akkayasamy Kowsalya Uma Ramalingam Sameer Chaudhary Mahesh Kumar |
| author_sort | Akkayasamy Kowsalya |
| collection | DOAJ |
| description | Purpose: Optic neuritis, defined as inflammation of the optic nerve, is the most common optic neuropathy affecting adults. Various studies in Southeast Asia have shown that the clinical profile of optic neuritis might differ in these regions from that reported in the western literature. Through this study, we evaluate the clinical profile of pediatric optic neuritis (PON) in the Indian population. Methods: This was a hospital-based prospective observational study. Patients with optic neuritis younger than 16 years who attended the neuro-ophthalmology clinic from May 2016 to April 2017 were included in the study. Results: This study included 54 eyes of 38 patients. The mean age of presentation was 10.6 years. Unilateral disease (58%) was found to be more common, and a slight female preponderance (58%) was noted. The most common feature was visual loss (96.3%). Pupillary light reflex abnormality was seen in most patients. Fundus examination revealed disk edema (77.7%) to be the most common feature. Neuroimaging was performed in 34 patients, and multiple sclerosis was diagnosed in four patients. At 3 months follow-up after treatment, 89% of eyes had best correct visual acuity of 6/9 or better (P < 0.001). Conclusion: In our study, we found the clinical profile of PON to be similar to that seen in western studies as well as those done previously in the Indian population, although with a few differences. |
| first_indexed | 2024-03-12T22:31:15Z |
| format | Article |
| id | doaj.art-0ea7fd2776814c0eaba9ac5d3efb5d77 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-03-12T22:31:15Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-0ea7fd2776814c0eaba9ac5d3efb5d772023-07-21T15:04:35ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892023-01-0171263764210.4103/ijo.IJO_1407_22Clinical features and visual outcomes of pediatric optic neuritis in the Indian population: A prospective studyAkkayasamy KowsalyaUma RamalingamSameer ChaudharyMahesh KumarPurpose: Optic neuritis, defined as inflammation of the optic nerve, is the most common optic neuropathy affecting adults. Various studies in Southeast Asia have shown that the clinical profile of optic neuritis might differ in these regions from that reported in the western literature. Through this study, we evaluate the clinical profile of pediatric optic neuritis (PON) in the Indian population. Methods: This was a hospital-based prospective observational study. Patients with optic neuritis younger than 16 years who attended the neuro-ophthalmology clinic from May 2016 to April 2017 were included in the study. Results: This study included 54 eyes of 38 patients. The mean age of presentation was 10.6 years. Unilateral disease (58%) was found to be more common, and a slight female preponderance (58%) was noted. The most common feature was visual loss (96.3%). Pupillary light reflex abnormality was seen in most patients. Fundus examination revealed disk edema (77.7%) to be the most common feature. Neuroimaging was performed in 34 patients, and multiple sclerosis was diagnosed in four patients. At 3 months follow-up after treatment, 89% of eyes had best correct visual acuity of 6/9 or better (P < 0.001). Conclusion: In our study, we found the clinical profile of PON to be similar to that seen in western studies as well as those done previously in the Indian population, although with a few differences.http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=2;spage=637;epage=642;aulast=Kowsalyademyelinationindian populationmultiple sclerosisoptic neuritispediatric optic neuritis |
| spellingShingle | Akkayasamy Kowsalya Uma Ramalingam Sameer Chaudhary Mahesh Kumar Clinical features and visual outcomes of pediatric optic neuritis in the Indian population: A prospective study Indian Journal of Ophthalmology demyelination indian population multiple sclerosis optic neuritis pediatric optic neuritis |
| title | Clinical features and visual outcomes of pediatric optic neuritis in the Indian population: A prospective study |
| title_full | Clinical features and visual outcomes of pediatric optic neuritis in the Indian population: A prospective study |
| title_fullStr | Clinical features and visual outcomes of pediatric optic neuritis in the Indian population: A prospective study |
| title_full_unstemmed | Clinical features and visual outcomes of pediatric optic neuritis in the Indian population: A prospective study |
| title_short | Clinical features and visual outcomes of pediatric optic neuritis in the Indian population: A prospective study |
| title_sort | clinical features and visual outcomes of pediatric optic neuritis in the indian population a prospective study |
| topic | demyelination indian population multiple sclerosis optic neuritis pediatric optic neuritis |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=2;spage=637;epage=642;aulast=Kowsalya |
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