Role of galectin 3 and epicardial fat thickness in the development of atrial fibrillation in patients with metabolic syndrome
Objective. To evaluate the epicardial fat thickness (EFT) in patients with metabolic syndrome (MS), including paroxysmal and persistent atrial fibrillation (AF). To relate EFT to the fibroid heart marker, i.e. galectin 3. Materials and methods. We examined 100 patients with MS (50 with AF), and 50 h...
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| Format: | Article |
| Language: | Russian |
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Academician I.P. Pavlov First St. Petersburg State Medical University
2015-03-01
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| Series: | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
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| Online Access: | https://www.sci-notes.ru/jour/article/view/110 |
| _version_ | 1797700281781190656 |
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| author | V. A. Ionin O. V. Listopad S. E. Nifontov E. I. Baranova A. V. Soboleva E. V. Shlyakhto |
| author_facet | V. A. Ionin O. V. Listopad S. E. Nifontov E. I. Baranova A. V. Soboleva E. V. Shlyakhto |
| author_sort | V. A. Ionin |
| collection | DOAJ |
| description | Objective. To evaluate the epicardial fat thickness (EFT) in patients with metabolic syndrome (MS), including paroxysmal and persistent atrial fibrillation (AF). To relate EFT to the fibroid heart marker, i.e. galectin 3. Materials and methods. We examined 100 patients with MS (50 with AF), and 50 healthy persons made the control group. Serum galectin 3 was measured by ELISA method. The EFT was measured with echocardiography. Results. EFT in patients with MS was twofold higher than in healthy persons. EFT in patients with MS and AF didn't differ significantly from that in patients with MS without AF. Positive correlation between the levels of EFT and galectin 3 in serum was revealed. Serum galectin 3 and EFT were associated with atrial fibrillation in patients with MS (OR:1,27, 95% CI 1,02-1,58 and OR:1,73, 95% CI 1,37-2,19, correspondingly).Conclusion. Definition of EFT at echocardiography can be used in the assessment of risk AF in patients with MS. |
| first_indexed | 2024-03-12T04:20:35Z |
| format | Article |
| id | doaj.art-0eac1589612c408db5aa941c178f12f5 |
| institution | Directory Open Access Journal |
| issn | 1607-4181 |
| language | Russian |
| last_indexed | 2024-03-12T04:20:35Z |
| publishDate | 2015-03-01 |
| publisher | Academician I.P. Pavlov First St. Petersburg State Medical University |
| record_format | Article |
| series | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
| spelling | doaj.art-0eac1589612c408db5aa941c178f12f52023-09-03T10:33:25ZrusAcademician I.P. Pavlov First St. Petersburg State Medical UniversityУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова1607-41812015-03-01221434610.24884/1607-4181-2015-22-1-43-46106Role of galectin 3 and epicardial fat thickness in the development of atrial fibrillation in patients with metabolic syndromeV. A. Ionin0O. V. Listopad1S. E. Nifontov2E. I. Baranova3A. V. Soboleva4E. V. Shlyakhto5Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. ПавловаПервый Санкт-Петербургский государственный медицинский университет имени академика И. П. ПавловаПервый Санкт-Петербургский государственный медицинский университет имени академика И. П. ПавловаПервый Санкт-Петербургский государственный медицинский университет имени академика И. П. ПавловаПервый Санкт-Петербургский государственный медицинский университет имени академика И. П. ПавловаПервый Санкт-Петербургский государственный медицинский университет имени академика И. П. ПавловаObjective. To evaluate the epicardial fat thickness (EFT) in patients with metabolic syndrome (MS), including paroxysmal and persistent atrial fibrillation (AF). To relate EFT to the fibroid heart marker, i.e. galectin 3. Materials and methods. We examined 100 patients with MS (50 with AF), and 50 healthy persons made the control group. Serum galectin 3 was measured by ELISA method. The EFT was measured with echocardiography. Results. EFT in patients with MS was twofold higher than in healthy persons. EFT in patients with MS and AF didn't differ significantly from that in patients with MS without AF. Positive correlation between the levels of EFT and galectin 3 in serum was revealed. Serum galectin 3 and EFT were associated with atrial fibrillation in patients with MS (OR:1,27, 95% CI 1,02-1,58 and OR:1,73, 95% CI 1,37-2,19, correspondingly).Conclusion. Definition of EFT at echocardiography can be used in the assessment of risk AF in patients with MS.https://www.sci-notes.ru/jour/article/view/110галектин-3толщина эпикардиального жираметаболический синдромфибрилляция предсердийgalectin 3epicardial fat thicknessmetabolic syndromeatrial fibrillation |
| spellingShingle | V. A. Ionin O. V. Listopad S. E. Nifontov E. I. Baranova A. V. Soboleva E. V. Shlyakhto Role of galectin 3 and epicardial fat thickness in the development of atrial fibrillation in patients with metabolic syndrome Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова галектин-3 толщина эпикардиального жира метаболический синдром фибрилляция предсердий galectin 3 epicardial fat thickness metabolic syndrome atrial fibrillation |
| title | Role of galectin 3 and epicardial fat thickness in the development of atrial fibrillation in patients with metabolic syndrome |
| title_full | Role of galectin 3 and epicardial fat thickness in the development of atrial fibrillation in patients with metabolic syndrome |
| title_fullStr | Role of galectin 3 and epicardial fat thickness in the development of atrial fibrillation in patients with metabolic syndrome |
| title_full_unstemmed | Role of galectin 3 and epicardial fat thickness in the development of atrial fibrillation in patients with metabolic syndrome |
| title_short | Role of galectin 3 and epicardial fat thickness in the development of atrial fibrillation in patients with metabolic syndrome |
| title_sort | role of galectin 3 and epicardial fat thickness in the development of atrial fibrillation in patients with metabolic syndrome |
| topic | галектин-3 толщина эпикардиального жира метаболический синдром фибрилляция предсердий galectin 3 epicardial fat thickness metabolic syndrome atrial fibrillation |
| url | https://www.sci-notes.ru/jour/article/view/110 |
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