The Short‐Term Effects and Burden of Ambient Air Pollution on Hospitalization for Type 2 Diabetes: Time‐Stratified Case‐Crossover Evidence From Sichuan, China
Abstract Type 2 diabetes mellitus (T2DM), a complicated metabolic disease, might be developed or exacerbated by air pollution, resulting in economic and health burden to patients. So far, limited studies have estimated associations between short‐term exposure to air pollution and disease burden of T...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Geophysical Union (AGU)
2023-11-01
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| Series: | GeoHealth |
| Subjects: | |
| Online Access: | https://doi.org/10.1029/2023GH000846 |
| _version_ | 1797449737356443648 |
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| author | Wanyanhan Jiang Han Chen Hongwei Li Yuelin Zhou Mengxue Xie Chengchao Zhou Lian Yang |
| author_facet | Wanyanhan Jiang Han Chen Hongwei Li Yuelin Zhou Mengxue Xie Chengchao Zhou Lian Yang |
| author_sort | Wanyanhan Jiang |
| collection | DOAJ |
| description | Abstract Type 2 diabetes mellitus (T2DM), a complicated metabolic disease, might be developed or exacerbated by air pollution, resulting in economic and health burden to patients. So far, limited studies have estimated associations between short‐term exposure to air pollution and disease burden of T2DM in China. Hence, we aimed to estimate the associations and burden of ambient air pollutants (NO2, PM10, PM2.5, SO2, and CO) on hospital admissions (HAs) for T2DM using a time‐stratified case‐crossover design. Data on HAs for T2DM during 2017–2019 were collected from hospital electronic health records in nine cities in Sichuan Province using conditional poisson regression. Totally, 92,381 T2DM hospitalizations were recorded. There were significant short‐term effects of NO2, PM10, PM2.5, SO2 and CO on HAs for T2DM. A 10 μg/m3 increment of NO2, PM10, PM2.5, SO2 and CO as linked with a 3.39% (95% CI: 2.26%, 4.54%), 0.33% (95% CI: 0.04%, 0.62%), 0.76% (95% CI: 0.35%, 1.16%), 12.68% (95% CI: 8.14%, 17.42%) and 79.00% (95% CI: 39.81%, 129.18%) increase in HAs for T2DM at lag 6. Stratified analyses modified by age, sex, and season showed old (≥65 years) and female patients linked with higher impacts. Using WHO's air quality guidelines of NO2, PM10, PM2.5, and CO as the reference, the attributable number of T2DM HAs exceeding these pollutants exposures were 786, 323, 793, and 2,127 during 2017–2019. Besides, the total medical costs of 25.83, 10.54, 30.74, and 67.78 million China Yuan were attributed to NO2, PM10, PM2.5, and CO. In conclusion, short‐term exposures to air pollutants were associated with higher risks of HAs for T2DM. |
| first_indexed | 2024-03-09T14:29:25Z |
| format | Article |
| id | doaj.art-0ead23472e414e5a946b104af27f3cbe |
| institution | Directory Open Access Journal |
| issn | 2471-1403 |
| language | English |
| last_indexed | 2024-03-09T14:29:25Z |
| publishDate | 2023-11-01 |
| publisher | American Geophysical Union (AGU) |
| record_format | Article |
| series | GeoHealth |
| spelling | doaj.art-0ead23472e414e5a946b104af27f3cbe2023-11-28T02:35:46ZengAmerican Geophysical Union (AGU)GeoHealth2471-14032023-11-01711n/an/a10.1029/2023GH000846The Short‐Term Effects and Burden of Ambient Air Pollution on Hospitalization for Type 2 Diabetes: Time‐Stratified Case‐Crossover Evidence From Sichuan, ChinaWanyanhan Jiang0Han Chen1Hongwei Li2Yuelin Zhou3Mengxue Xie4Chengchao Zhou5Lian Yang6School of Public Health Chengdu University of Traditional Chinese Medicine Chengdu Sichuan ChinaSichuan Wanhao Consulting Co., Ltd Chengdu Sichuan ChinaSchool of Public Health Chengdu University of Traditional Chinese Medicine Chengdu Sichuan ChinaSchool of Public Health Chengdu University of Traditional Chinese Medicine Chengdu Sichuan ChinaSchool of Public Health Chengdu University of Traditional Chinese Medicine Chengdu Sichuan ChinaCentre for Health Management and Policy Research School of Public Health College of Medicine Shandong University Jinan ChinaSchool of Public Health Chengdu University of Traditional Chinese Medicine Chengdu Sichuan ChinaAbstract Type 2 diabetes mellitus (T2DM), a complicated metabolic disease, might be developed or exacerbated by air pollution, resulting in economic and health burden to patients. So far, limited studies have estimated associations between short‐term exposure to air pollution and disease burden of T2DM in China. Hence, we aimed to estimate the associations and burden of ambient air pollutants (NO2, PM10, PM2.5, SO2, and CO) on hospital admissions (HAs) for T2DM using a time‐stratified case‐crossover design. Data on HAs for T2DM during 2017–2019 were collected from hospital electronic health records in nine cities in Sichuan Province using conditional poisson regression. Totally, 92,381 T2DM hospitalizations were recorded. There were significant short‐term effects of NO2, PM10, PM2.5, SO2 and CO on HAs for T2DM. A 10 μg/m3 increment of NO2, PM10, PM2.5, SO2 and CO as linked with a 3.39% (95% CI: 2.26%, 4.54%), 0.33% (95% CI: 0.04%, 0.62%), 0.76% (95% CI: 0.35%, 1.16%), 12.68% (95% CI: 8.14%, 17.42%) and 79.00% (95% CI: 39.81%, 129.18%) increase in HAs for T2DM at lag 6. Stratified analyses modified by age, sex, and season showed old (≥65 years) and female patients linked with higher impacts. Using WHO's air quality guidelines of NO2, PM10, PM2.5, and CO as the reference, the attributable number of T2DM HAs exceeding these pollutants exposures were 786, 323, 793, and 2,127 during 2017–2019. Besides, the total medical costs of 25.83, 10.54, 30.74, and 67.78 million China Yuan were attributed to NO2, PM10, PM2.5, and CO. In conclusion, short‐term exposures to air pollutants were associated with higher risks of HAs for T2DM.https://doi.org/10.1029/2023GH000846air pollutionhospital admissionsattributable economic costtype 2 diabetes mellitus |
| spellingShingle | Wanyanhan Jiang Han Chen Hongwei Li Yuelin Zhou Mengxue Xie Chengchao Zhou Lian Yang The Short‐Term Effects and Burden of Ambient Air Pollution on Hospitalization for Type 2 Diabetes: Time‐Stratified Case‐Crossover Evidence From Sichuan, China GeoHealth air pollution hospital admissions attributable economic cost type 2 diabetes mellitus |
| title | The Short‐Term Effects and Burden of Ambient Air Pollution on Hospitalization for Type 2 Diabetes: Time‐Stratified Case‐Crossover Evidence From Sichuan, China |
| title_full | The Short‐Term Effects and Burden of Ambient Air Pollution on Hospitalization for Type 2 Diabetes: Time‐Stratified Case‐Crossover Evidence From Sichuan, China |
| title_fullStr | The Short‐Term Effects and Burden of Ambient Air Pollution on Hospitalization for Type 2 Diabetes: Time‐Stratified Case‐Crossover Evidence From Sichuan, China |
| title_full_unstemmed | The Short‐Term Effects and Burden of Ambient Air Pollution on Hospitalization for Type 2 Diabetes: Time‐Stratified Case‐Crossover Evidence From Sichuan, China |
| title_short | The Short‐Term Effects and Burden of Ambient Air Pollution on Hospitalization for Type 2 Diabetes: Time‐Stratified Case‐Crossover Evidence From Sichuan, China |
| title_sort | short term effects and burden of ambient air pollution on hospitalization for type 2 diabetes time stratified case crossover evidence from sichuan china |
| topic | air pollution hospital admissions attributable economic cost type 2 diabetes mellitus |
| url | https://doi.org/10.1029/2023GH000846 |
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