Bromodomain and extra-terminal motif proteins regulate linear and circular pvt1 in acute myeloid leukemia cells under normoxi and hypoxia

INTRODUCTION: Bromodomain and extra-terminal motif-protein inhibitors (BETi) have shown an antileukemic effect in several subtypes of acute myeloid leukemia (AML), both in vitro and in vivo (Daniel Gerlach et al. 2018 Oncogene). The effect of BETi is mainly mediated by suppression of bromodomain-con...

Full description

Bibliographic Details
Main Authors: M. Ghetti, I. Vannini, S. Bruno, C. Liverani, D. Traversa, L. Montanaro, R. Napolitano, A. Ghelli Luserna di Rorà, T. Ibrahim, C.T. Storlazzi, G. Martinelli, G. Simonetti
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Hematology Reports
Online Access:https://www.pagepress.org/journals/index.php/hr/article/view/8909

Similar Items