Bromodomain and extra-terminal motif proteins regulate linear and circular pvt1 in acute myeloid leukemia cells under normoxi and hypoxia
INTRODUCTION: Bromodomain and extra-terminal motif-protein inhibitors (BETi) have shown an antileukemic effect in several subtypes of acute myeloid leukemia (AML), both in vitro and in vivo (Daniel Gerlach et al. 2018 Oncogene). The effect of BETi is mainly mediated by suppression of bromodomain-con...
Main Authors: | M. Ghetti, I. Vannini, S. Bruno, C. Liverani, D. Traversa, L. Montanaro, R. Napolitano, A. Ghelli Luserna di Rorà, T. Ibrahim, C.T. Storlazzi, G. Martinelli, G. Simonetti |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-09-01
|
Series: | Hematology Reports |
Online Access: | https://www.pagepress.org/journals/index.php/hr/article/view/8909 |
Similar Items
-
Uncovering the expression of circPVT1 in the extracellular vesicles of acute myeloid leukemia patients
by: Martina Ghetti, et al.
Published: (2023-09-01) -
Targeting Proliferation Signals and the Cell Cycle Machinery in Acute Leukemias: Novel Molecules on the Horizon
by: Andrea Ghelli Luserna di Rorà, et al.
Published: (2023-01-01) -
77232 The role of the bromodomain and extra-terminal motif (BET) family of proteins in head and neck cancer tumorigenic phenotype
by: Reilly A. Sample, et al.
Published: (2021-03-01) -
Venetoclax durable response in adult relapsed/refractory Philadelphia-negative acute lymphoblastic leukemia with JAK/STAT pathway alterations
by: Anna Ferrari, et al.
Published: (2023-05-01) -
Roles of Bromodomain Extra Terminal Proteins in Metabolic Signaling and Diseases
by: Dayu Wu, et al.
Published: (2022-08-01)