Quantification of Non-Motor Symptoms in Parkinsonian Cynomolgus Monkeys

Quantification of Non-Motor Symptoms in Parkinsonian Cynomolgus Monkeys

Background: Parkinson’s disease (PD) is a neurodegenerative disorder that features motor and non-motor deficits. The use of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopamine neuron degeneration has been widely practiced to produce reliable animal models of PD. However, most previo...

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Bibliographic Details
Main Authors: Yu Bao, Chaoning Gan, Zuyue Chen, Zhongquan Qi, Zhiqiang Meng, Feng Yue
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Brain Sciences
Subjects:
Parkinson’s
monkey
non-motor symptoms
anxiety
sleep
cognition
Online Access:https://www.mdpi.com/2076-3425/13/8/1153

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