(Z)-N′-(3-Ethyl-4-oxothiazolidin-2-ylidene)-2-[6-(4-methoxyphenyl)imidazo[2,1-b]thiazol-3-yl]acetohydrazide
The title compound, C19H19N5O3S2, crystallizes in the triclinic space group P-1, with two independent molecules (A and B) in the asymmetric unit (Z′ = 2). The imidazo[2,1-b][1,3]thiazole ring systems in molecules A and B are essentially planar (r.m.s deviations = 0.004 and 0.005 Å, respectively), wi...
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| Format: | Article |
| Language: | English |
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International Union of Crystallography
2017-01-01
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| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S2414314617000402 |
| _version_ | 1811277360204349440 |
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| author | Zeliha Atioğlu Mehmet Akkurt Faika Başoğlu Nuray Ulusoy Güzeldemirci Rahmi Köseoğlu Cem Cüneyt Ersanlı |
| author_facet | Zeliha Atioğlu Mehmet Akkurt Faika Başoğlu Nuray Ulusoy Güzeldemirci Rahmi Köseoğlu Cem Cüneyt Ersanlı |
| author_sort | Zeliha Atioğlu |
| collection | DOAJ |
| description | The title compound, C19H19N5O3S2, crystallizes in the triclinic space group P-1, with two independent molecules (A and B) in the asymmetric unit (Z′ = 2). The imidazo[2,1-b][1,3]thiazole ring systems in molecules A and B are essentially planar (r.m.s deviations = 0.004 and 0.005 Å, respectively), with dihedral angles of 1.1 (3) and 0.8 (3)°, respectively, between the thiazole and imidazole rings. The mean planes of these ring systems make dihedral angles of 16.0 (2) and 61.9 (2)° for molecule A, and 11.8 (2) and 74.3 (2)° for molecule B, with the 1,3-thiazolidine and methoxy-substituted benzene rings, respectively. In the crystal, molecules are linked via N—H...O hydrogen bonds, forming –A–B–A–B– chains along [100]. The chains are linked by C—H...O hydrogen bonds, forming layers parallel to the ab plane. |
| first_indexed | 2024-04-13T00:14:18Z |
| format | Article |
| id | doaj.art-0eb15afa7d124079904f76ee1c5882c9 |
| institution | Directory Open Access Journal |
| issn | 2414-3146 |
| language | English |
| last_indexed | 2024-04-13T00:14:18Z |
| publishDate | 2017-01-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | IUCrData |
| spelling | doaj.art-0eb15afa7d124079904f76ee1c5882c92022-12-22T03:10:58ZengInternational Union of CrystallographyIUCrData2414-31462017-01-0121x17004010.1107/S2414314617000402su4123(Z)-N′-(3-Ethyl-4-oxothiazolidin-2-ylidene)-2-[6-(4-methoxyphenyl)imidazo[2,1-b]thiazol-3-yl]acetohydrazideZeliha Atioğlu0Mehmet Akkurt1Faika Başoğlu2Nuray Ulusoy Güzeldemirci3Rahmi Köseoğlu4Cem Cüneyt Ersanlı5İlke Education and Health Foundation, Cappadocia Vocational College, The Medical Imaging Techniques Program, 50420 Mustafapaşa, Ürgüp, Nevşehir, TurkeyDepartment of Physics, Faculty of Sciences, Erciyes University, 38039 Kayseri, TurkeyDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Istanbul, 34116 Beyazıt, Istanbul, TurkeyDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Istanbul, 34116 Beyazıt, Istanbul, TurkeyDepartment of Physics, Faculty of Sciences, Erciyes University, 38039 Kayseri, TurkeyDepartment of Physics, Faculty of Arts and Sciences, Sinop University, 57010 Sinop, TurkeyThe title compound, C19H19N5O3S2, crystallizes in the triclinic space group P-1, with two independent molecules (A and B) in the asymmetric unit (Z′ = 2). The imidazo[2,1-b][1,3]thiazole ring systems in molecules A and B are essentially planar (r.m.s deviations = 0.004 and 0.005 Å, respectively), with dihedral angles of 1.1 (3) and 0.8 (3)°, respectively, between the thiazole and imidazole rings. The mean planes of these ring systems make dihedral angles of 16.0 (2) and 61.9 (2)° for molecule A, and 11.8 (2) and 74.3 (2)° for molecule B, with the 1,3-thiazolidine and methoxy-substituted benzene rings, respectively. In the crystal, molecules are linked via N—H...O hydrogen bonds, forming –A–B–A–B– chains along [100]. The chains are linked by C—H...O hydrogen bonds, forming layers parallel to the ab plane.http://scripts.iucr.org/cgi-bin/paper?S2414314617000402crystal structurethiazole ringimidazole ringimidazo[2,1-b][1,3]thiazole ring systemthiazolidine ringhydrogen bonding |
| spellingShingle | Zeliha Atioğlu Mehmet Akkurt Faika Başoğlu Nuray Ulusoy Güzeldemirci Rahmi Köseoğlu Cem Cüneyt Ersanlı (Z)-N′-(3-Ethyl-4-oxothiazolidin-2-ylidene)-2-[6-(4-methoxyphenyl)imidazo[2,1-b]thiazol-3-yl]acetohydrazide IUCrData crystal structure thiazole ring imidazole ring imidazo[2,1-b][1,3]thiazole ring system thiazolidine ring hydrogen bonding |
| title | (Z)-N′-(3-Ethyl-4-oxothiazolidin-2-ylidene)-2-[6-(4-methoxyphenyl)imidazo[2,1-b]thiazol-3-yl]acetohydrazide |
| title_full | (Z)-N′-(3-Ethyl-4-oxothiazolidin-2-ylidene)-2-[6-(4-methoxyphenyl)imidazo[2,1-b]thiazol-3-yl]acetohydrazide |
| title_fullStr | (Z)-N′-(3-Ethyl-4-oxothiazolidin-2-ylidene)-2-[6-(4-methoxyphenyl)imidazo[2,1-b]thiazol-3-yl]acetohydrazide |
| title_full_unstemmed | (Z)-N′-(3-Ethyl-4-oxothiazolidin-2-ylidene)-2-[6-(4-methoxyphenyl)imidazo[2,1-b]thiazol-3-yl]acetohydrazide |
| title_short | (Z)-N′-(3-Ethyl-4-oxothiazolidin-2-ylidene)-2-[6-(4-methoxyphenyl)imidazo[2,1-b]thiazol-3-yl]acetohydrazide |
| title_sort | z n 3 ethyl 4 oxothiazolidin 2 ylidene 2 6 4 methoxyphenyl imidazo 2 1 b thiazol 3 yl acetohydrazide |
| topic | crystal structure thiazole ring imidazole ring imidazo[2,1-b][1,3]thiazole ring system thiazolidine ring hydrogen bonding |
| url | http://scripts.iucr.org/cgi-bin/paper?S2414314617000402 |
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