Design on antibacterial and cytocompatible TiO2-CuxO/Ag coating through regulation of ions release
Developing antibacterial and biocompatible coatings remains a challenge. A promising new thought is addressed to control the ion release behaviors through the design of the phases, structures, and morphologies of the products. In this study, TiO2-CuxO/Ag coatings were prepared via co-sputtering comb...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-05-01
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| Series: | Journal of Materials Research and Technology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2238785424008330 |
| _version_ | 1827216587774492672 |
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| author | Junqiang Wang Yan Zhu Guodong Zhang Jinkun Liu Tao Shen Xinyuan Wei |
| author_facet | Junqiang Wang Yan Zhu Guodong Zhang Jinkun Liu Tao Shen Xinyuan Wei |
| author_sort | Junqiang Wang |
| collection | DOAJ |
| description | Developing antibacterial and biocompatible coatings remains a challenge. A promising new thought is addressed to control the ion release behaviors through the design of the phases, structures, and morphologies of the products. In this study, TiO2-CuxO/Ag coatings were prepared via co-sputtering combined with annealing, the changes brought by different annealing temperatures were characterized, the physical, electrochemical, and antibacterial properties were concerned, and the relationship between biological performance and ions-releasing behavior was investigated. Results showed that the TiO2-CuxO/Ag coatings performed the morphologies of larger Ag particles seeded like islands on the dense CuO, such features improved the hydrophilicity and corrosion resistance of the Ti substrate. Rising the annealing temperature further enhanced the surface roughness, hydrophilicity, Young's modulus, hardness, and dynamic coefficient of friction of the coatings. Within the initial 3 h of soaking, both metal ions contributed to playing the antibacterial roles and produced a synergistic enhancement effect to satisfy the reduction of Staphylococcus aureus to 99.9%. In the next 3–120 h soaking, Ag releasing was suppressed and Cu releasing maintained its slow and stable trend, which made sure that the MC3T3-E1 cells could proliferate and adhere on the negatively charged coating surface, and copper oxide nanoparticles were phagocytized by cells. Among all TiO2-CuxO/Ag coatings, the M500 sample displayed superior performances on the surface roughness, contact angle, mechanical Young's modulus, and surface hardness, also realized the aim of killing pathogenic bacteria first and then activating cell survival, which enabled it to be potentially applied in clinical treatment. |
| first_indexed | 2024-04-24T07:38:05Z |
| format | Article |
| id | doaj.art-0eb2b95361c446acbdbd330ca9f01339 |
| institution | Directory Open Access Journal |
| issn | 2238-7854 |
| language | English |
| last_indexed | 2025-03-21T15:05:30Z |
| publishDate | 2024-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Materials Research and Technology |
| spelling | doaj.art-0eb2b95361c446acbdbd330ca9f013392024-06-20T06:53:31ZengElsevierJournal of Materials Research and Technology2238-78542024-05-013037663779Design on antibacterial and cytocompatible TiO2-CuxO/Ag coating through regulation of ions releaseJunqiang Wang0Yan Zhu1Guodong Zhang2Jinkun Liu3Tao Shen4Xinyuan Wei5Faculty of Materials Science and Technology, Kunming University of Science and Technology, Kunming, 650093, China; School of Materials Science and Engineering, Shanghai University, No. 99, Shangda Road, Baoshan District, Shanghai, 200072, ChinaFaculty of Materials Science and Technology, Kunming University of Science and Technology, Kunming, 650093, China; Corresponding author. Faculty of Materials Science and Technology, Kunming University of Science and Technology, No. 68, Wenchang Road, Lianhua Campus, Kunming, Yunnan, 650093, China.Faculty of Materials Science and Technology, Kunming University of Science and Technology, Kunming, 650093, ChinaFaculty of Materials Science and Technology, Kunming University of Science and Technology, Kunming, 650093, China; Corresponding author. Faculty of Materials Science and Technology, Kunming University of Science and Technology, No. 68, Wenchang Road, Lianhua Campus, Kunming, Yunnan, 650093, China.Faculty of Materials Science and Technology, Kunming University of Science and Technology, Kunming, 650093, China; Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, 650500, ChinaState Key Laboratory of Surface Physics and Key Laboratory for Computational Physical Sciences & Department of Physics, Fudan University, Shanghai, 200433, ChinaDeveloping antibacterial and biocompatible coatings remains a challenge. A promising new thought is addressed to control the ion release behaviors through the design of the phases, structures, and morphologies of the products. In this study, TiO2-CuxO/Ag coatings were prepared via co-sputtering combined with annealing, the changes brought by different annealing temperatures were characterized, the physical, electrochemical, and antibacterial properties were concerned, and the relationship between biological performance and ions-releasing behavior was investigated. Results showed that the TiO2-CuxO/Ag coatings performed the morphologies of larger Ag particles seeded like islands on the dense CuO, such features improved the hydrophilicity and corrosion resistance of the Ti substrate. Rising the annealing temperature further enhanced the surface roughness, hydrophilicity, Young's modulus, hardness, and dynamic coefficient of friction of the coatings. Within the initial 3 h of soaking, both metal ions contributed to playing the antibacterial roles and produced a synergistic enhancement effect to satisfy the reduction of Staphylococcus aureus to 99.9%. In the next 3–120 h soaking, Ag releasing was suppressed and Cu releasing maintained its slow and stable trend, which made sure that the MC3T3-E1 cells could proliferate and adhere on the negatively charged coating surface, and copper oxide nanoparticles were phagocytized by cells. Among all TiO2-CuxO/Ag coatings, the M500 sample displayed superior performances on the surface roughness, contact angle, mechanical Young's modulus, and surface hardness, also realized the aim of killing pathogenic bacteria first and then activating cell survival, which enabled it to be potentially applied in clinical treatment.http://www.sciencedirect.com/science/article/pii/S2238785424008330Magnetron sputteringTiO2-CuxO/Ag multifunctional coatingSynergistic actionAntibacterial activityCell proliferationIons release behaviors |
| spellingShingle | Junqiang Wang Yan Zhu Guodong Zhang Jinkun Liu Tao Shen Xinyuan Wei Design on antibacterial and cytocompatible TiO2-CuxO/Ag coating through regulation of ions release Journal of Materials Research and Technology Magnetron sputtering TiO2-CuxO/Ag multifunctional coating Synergistic action Antibacterial activity Cell proliferation Ions release behaviors |
| title | Design on antibacterial and cytocompatible TiO2-CuxO/Ag coating through regulation of ions release |
| title_full | Design on antibacterial and cytocompatible TiO2-CuxO/Ag coating through regulation of ions release |
| title_fullStr | Design on antibacterial and cytocompatible TiO2-CuxO/Ag coating through regulation of ions release |
| title_full_unstemmed | Design on antibacterial and cytocompatible TiO2-CuxO/Ag coating through regulation of ions release |
| title_short | Design on antibacterial and cytocompatible TiO2-CuxO/Ag coating through regulation of ions release |
| title_sort | design on antibacterial and cytocompatible tio2 cuxo ag coating through regulation of ions release |
| topic | Magnetron sputtering TiO2-CuxO/Ag multifunctional coating Synergistic action Antibacterial activity Cell proliferation Ions release behaviors |
| url | http://www.sciencedirect.com/science/article/pii/S2238785424008330 |
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