METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis
Methyltransferase-like 3 (METTL3) and N6-methyladenosine (m6A) are involved in many types of biological and pathological processes, including DNA repair. However, the function and mechanism of METTL3 in DNA repair and chemotherapeutic response remain largely unknown. In present study, we identified...
Main Authors: | Enjie Li, Mingyue Xia, Yu Du, Kaili Long, Feng Ji, Feiyan Pan, Lingfeng He, Zhigang Hu, Zhigang Guo |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-05-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/75231 |
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