Electrochemical Hybrid Methods and Sensors for Antioxidant/Oxidant Activity Monitoring and Their Use as a Diagnostic Tool of Oxidative Stress: Future Perspectives and Challenges

The terminology used in electrochemical methods which are used to generate the measured signal in antioxidant/oxidant activity (AOA/OA) sensors is briefly considered. The review presents a hybrid version of electrochemical methods for the determination of AOA/OA. Invasive electrochemical methods/sen...

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Main Authors: Khiena Z. Brainina, Yan E. Kazakov
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Chemosensors
Subjects:
Online Access:https://www.mdpi.com/2227-9040/8/4/90
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author Khiena Z. Brainina
Yan E. Kazakov
author_facet Khiena Z. Brainina
Yan E. Kazakov
author_sort Khiena Z. Brainina
collection DOAJ
description The terminology used in electrochemical methods which are used to generate the measured signal in antioxidant/oxidant activity (AOA/OA) sensors is briefly considered. The review presents a hybrid version of electrochemical methods for the determination of AOA/OA. Invasive electrochemical methods/sensors for AOA/OA of blood/serum/plasma, and non-invasive ones for semen, sweat, saliva and skin determination are described. AOA/OA sensors application in health estimation, cosmetology, food and nutrients is presented. Attention is paid to widely described approaches and technologies used in chemical/biochemical sensors. It will be considered as base/prototypes for developing sensors of the kind for AOA/OA determination. Prospects for the development of wearable, written sensors and biosensors are considered. Miniature and wireless sensors will allow for the monitoring of the patient’s state, both at the bedside and far beyond the hospital. The development of wearable self-powered written and printed sensors is an important step towards personalized medicine.
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spelling doaj.art-0ec0ab16ab1c4f289bee5813aa000e792023-11-20T15:12:36ZengMDPI AGChemosensors2227-90402020-09-01849010.3390/chemosensors8040090Electrochemical Hybrid Methods and Sensors for Antioxidant/Oxidant Activity Monitoring and Their Use as a Diagnostic Tool of Oxidative Stress: Future Perspectives and ChallengesKhiena Z. Brainina0Yan E. Kazakov1Sensors Technology Center, Ural State University of Economics, 62/45, 8 Marta/Narodnoi Voli St., Yekaterinburg 620144, RussiaSensors Technology Center, Ural State University of Economics, 62/45, 8 Marta/Narodnoi Voli St., Yekaterinburg 620144, RussiaThe terminology used in electrochemical methods which are used to generate the measured signal in antioxidant/oxidant activity (AOA/OA) sensors is briefly considered. The review presents a hybrid version of electrochemical methods for the determination of AOA/OA. Invasive electrochemical methods/sensors for AOA/OA of blood/serum/plasma, and non-invasive ones for semen, sweat, saliva and skin determination are described. AOA/OA sensors application in health estimation, cosmetology, food and nutrients is presented. Attention is paid to widely described approaches and technologies used in chemical/biochemical sensors. It will be considered as base/prototypes for developing sensors of the kind for AOA/OA determination. Prospects for the development of wearable, written sensors and biosensors are considered. Miniature and wireless sensors will allow for the monitoring of the patient’s state, both at the bedside and far beyond the hospital. The development of wearable self-powered written and printed sensors is an important step towards personalized medicine.https://www.mdpi.com/2227-9040/8/4/90sensorsantioxidant/oxidant activityoxidative stresshybrid electrochemical methodsbiofluids/tissue
spellingShingle Khiena Z. Brainina
Yan E. Kazakov
Electrochemical Hybrid Methods and Sensors for Antioxidant/Oxidant Activity Monitoring and Their Use as a Diagnostic Tool of Oxidative Stress: Future Perspectives and Challenges
Chemosensors
sensors
antioxidant/oxidant activity
oxidative stress
hybrid electrochemical methods
biofluids/tissue
title Electrochemical Hybrid Methods and Sensors for Antioxidant/Oxidant Activity Monitoring and Their Use as a Diagnostic Tool of Oxidative Stress: Future Perspectives and Challenges
title_full Electrochemical Hybrid Methods and Sensors for Antioxidant/Oxidant Activity Monitoring and Their Use as a Diagnostic Tool of Oxidative Stress: Future Perspectives and Challenges
title_fullStr Electrochemical Hybrid Methods and Sensors for Antioxidant/Oxidant Activity Monitoring and Their Use as a Diagnostic Tool of Oxidative Stress: Future Perspectives and Challenges
title_full_unstemmed Electrochemical Hybrid Methods and Sensors for Antioxidant/Oxidant Activity Monitoring and Their Use as a Diagnostic Tool of Oxidative Stress: Future Perspectives and Challenges
title_short Electrochemical Hybrid Methods and Sensors for Antioxidant/Oxidant Activity Monitoring and Their Use as a Diagnostic Tool of Oxidative Stress: Future Perspectives and Challenges
title_sort electrochemical hybrid methods and sensors for antioxidant oxidant activity monitoring and their use as a diagnostic tool of oxidative stress future perspectives and challenges
topic sensors
antioxidant/oxidant activity
oxidative stress
hybrid electrochemical methods
biofluids/tissue
url https://www.mdpi.com/2227-9040/8/4/90
work_keys_str_mv AT khienazbrainina electrochemicalhybridmethodsandsensorsforantioxidantoxidantactivitymonitoringandtheiruseasadiagnostictoolofoxidativestressfutureperspectivesandchallenges
AT yanekazakov electrochemicalhybridmethodsandsensorsforantioxidantoxidantactivitymonitoringandtheiruseasadiagnostictoolofoxidativestressfutureperspectivesandchallenges