Treatment of Virulent <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> and HIV Coinfected Macrophages with Gallium Nanoparticles Inhibits Pathogen Growth and Modulates Macrophage Cytokine Production

Treatment of Virulent <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> and HIV Coinfected Macrophages with Gallium Nanoparticles Inhibits Pathogen Growth and Modulates Macrophage Cytokine Production

ABSTRACT Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains a global threat. The course of TB is negatively impacted by coexistent infection with human immunodeficiency virus type 1 (HIV). Macrophage infection with these pathogens modulates their production of pro- and anti-inflammator...

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Bibliographic Details
Main Authors: Seoung-ryoung Choi, Bradley E. Britigan, Prabagaran Narayanasamy
Format: Article
Language:English
Published: American Society for Microbiology 2019-08-01
Series:mSphere
Subjects:
Mycobacterium tuberculosis
gallium
human immunodeficiency virus
iron metabolism
nanoparticle
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00443-19

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