Effect of Roux-en-Y gastric bypass in the control of erosive esophagitis

Background: Gastroesophageal reflux disease (GERD) is a multifactorial disease associated with environmental and genetic factors. Obesity is among the risk factors for its development, which also correlates with an increase in severity of clinical presentation and a higher incidence of complications...

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Main Authors: Antônio Benincá Albuquerque, André Luca Boeira Rovani, Bruna Schmitt Puhl, Carlos Roberto Giacometti, Eduardo Dombroski da Silva, Elisa Estivalete Jablonski, Fernanda Marcante Carlotto, Fernanda Tisott Burtet, Jaline Ribeiro da Silva, Larissa Belke, Carlos Augusto Scussel Madalosso, Daniel Navarini
Format: Article
Language:English
Published: Hospital de Clinicas de Porto Alegre ; Universidade Federal do Rio Grande do Sul (UFRGS) 2019-08-01
Series:Clinical and Biomedical Research
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Online Access:https://seer.ufrgs.br/hcpa/article/view/91178
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Summary:Background: Gastroesophageal reflux disease (GERD) is a multifactorial disease associated with environmental and genetic factors. Obesity is among the risk factors for its development, which also correlates with an increase in severity of clinical presentation and a higher incidence of complications associated with reflux. Aims: To evaluate the impact of Roux-en-Y gastric bypass on the control of erosive esophagitis and metabolic and anthropometric parameters related to obesity. Methods: This historical cohort study included a sample of 249 patients who had undergone bariatric surgery using the Roux-en-Y gastric bypass technique at the Hospital São Vicente de Paulo, Passo Fundo, southern Brazil, from January 2014 to December 2015. Results: Of 249 patients, 77.9% (190 patients) were female and the mean age was 38 years. The occurrence of reflux esophagitis was 81.1% (196 patients) in the preoperative period and 31.3% (75 patients) in the postoperative period. With regard to bariatric treatment response to control moderate and severe esophagitis (grades B, C and D), there was a reduction in prevalence from 62 (25%) to 12 (5%) patients (p<0.05).  Conclusion: Bariatric surgery using the Roux-en-Y gastric bypass technique is effective in the control of reflux esophagitis. Regression is observed mainly in cases of moderate and severe esophagitis. Keywords: Erosive esophagitis; GERD; bariatric surgery; obesity; comorbidity
ISSN:2357-9730