Vector competence of Anopheles quadrimaculatus and Aedes albopictus for genetically distinct Jamestown Canyon virus strains circulating in the Northeast United States
Abstract Background Jamestown Canyon virus (JCV; Peribunyaviridae, Orthobunyavirus) is a mosquito-borne pathogen belonging to the California serogroup. The virus is endemic in North America and increasingly recognized as a public health concern. In this study, we determined the vector competence of...
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| Format: | Article |
| Language: | English |
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BMC
2022-06-01
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| Series: | Parasites & Vectors |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13071-022-05342-3 |
| _version_ | 1828198186516217856 |
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| author | Constentin Dieme Laura D. Kramer Alexander T. Ciota |
| author_facet | Constentin Dieme Laura D. Kramer Alexander T. Ciota |
| author_sort | Constentin Dieme |
| collection | DOAJ |
| description | Abstract Background Jamestown Canyon virus (JCV; Peribunyaviridae, Orthobunyavirus) is a mosquito-borne pathogen belonging to the California serogroup. The virus is endemic in North America and increasingly recognized as a public health concern. In this study, we determined the vector competence of Anopheles (An.) quadrimaculatus and Aedes (Ae.) albopictus for five JCV strains belonging to the two lineages circulating in the Northeast. Methods An. quadrimaculatus and Ae. albopictus were fed blood meals containing two lineage A strains and three lineage B strains. Vector competence of both mosquito species was evaluated at 7- and 14-days post-feeding (dpf) by testing for virus presence in bodies, legs, and saliva. Results Our results demonstrated that Ae. albopictus mosquitoes are a competent vector for both lineages, with similar transmission levels for all strains tested. Variable levels of infection (46–83%) and dissemination (17–38%) were measured in An. quadrimaculatus, yet no transmission was detected for the five JCV strains evaluated. Conclusions Our results demonstrate that establishment of Ae. albopictus in the Northeast could increase the risk of JCV but suggest An. quadrimaculatus are not a competent vector for JCV. Graphical Abstract |
| first_indexed | 2024-04-12T10:33:20Z |
| format | Article |
| id | doaj.art-0ecfea68806b4ec2ace80e05fced091a |
| institution | Directory Open Access Journal |
| issn | 1756-3305 |
| language | English |
| last_indexed | 2024-04-12T10:33:20Z |
| publishDate | 2022-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Parasites & Vectors |
| spelling | doaj.art-0ecfea68806b4ec2ace80e05fced091a2022-12-22T03:36:47ZengBMCParasites & Vectors1756-33052022-06-011511610.1186/s13071-022-05342-3Vector competence of Anopheles quadrimaculatus and Aedes albopictus for genetically distinct Jamestown Canyon virus strains circulating in the Northeast United StatesConstentin Dieme0Laura D. Kramer1Alexander T. Ciota2Institut Pasteur de GuinéeWadsworth Center, New York State Department of HealthWadsworth Center, New York State Department of HealthAbstract Background Jamestown Canyon virus (JCV; Peribunyaviridae, Orthobunyavirus) is a mosquito-borne pathogen belonging to the California serogroup. The virus is endemic in North America and increasingly recognized as a public health concern. In this study, we determined the vector competence of Anopheles (An.) quadrimaculatus and Aedes (Ae.) albopictus for five JCV strains belonging to the two lineages circulating in the Northeast. Methods An. quadrimaculatus and Ae. albopictus were fed blood meals containing two lineage A strains and three lineage B strains. Vector competence of both mosquito species was evaluated at 7- and 14-days post-feeding (dpf) by testing for virus presence in bodies, legs, and saliva. Results Our results demonstrated that Ae. albopictus mosquitoes are a competent vector for both lineages, with similar transmission levels for all strains tested. Variable levels of infection (46–83%) and dissemination (17–38%) were measured in An. quadrimaculatus, yet no transmission was detected for the five JCV strains evaluated. Conclusions Our results demonstrate that establishment of Ae. albopictus in the Northeast could increase the risk of JCV but suggest An. quadrimaculatus are not a competent vector for JCV. Graphical Abstracthttps://doi.org/10.1186/s13071-022-05342-3Jamestown Canyon virusAedes albopictusAnopheles quadrimaculatusVector competence |
| spellingShingle | Constentin Dieme Laura D. Kramer Alexander T. Ciota Vector competence of Anopheles quadrimaculatus and Aedes albopictus for genetically distinct Jamestown Canyon virus strains circulating in the Northeast United States Parasites & Vectors Jamestown Canyon virus Aedes albopictus Anopheles quadrimaculatus Vector competence |
| title | Vector competence of Anopheles quadrimaculatus and Aedes albopictus for genetically distinct Jamestown Canyon virus strains circulating in the Northeast United States |
| title_full | Vector competence of Anopheles quadrimaculatus and Aedes albopictus for genetically distinct Jamestown Canyon virus strains circulating in the Northeast United States |
| title_fullStr | Vector competence of Anopheles quadrimaculatus and Aedes albopictus for genetically distinct Jamestown Canyon virus strains circulating in the Northeast United States |
| title_full_unstemmed | Vector competence of Anopheles quadrimaculatus and Aedes albopictus for genetically distinct Jamestown Canyon virus strains circulating in the Northeast United States |
| title_short | Vector competence of Anopheles quadrimaculatus and Aedes albopictus for genetically distinct Jamestown Canyon virus strains circulating in the Northeast United States |
| title_sort | vector competence of anopheles quadrimaculatus and aedes albopictus for genetically distinct jamestown canyon virus strains circulating in the northeast united states |
| topic | Jamestown Canyon virus Aedes albopictus Anopheles quadrimaculatus Vector competence |
| url | https://doi.org/10.1186/s13071-022-05342-3 |
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