Radiation-induced anaplastic astrocytoma following treatment of medulloblastoma
We hereby report a case of a 10-year-old girl in whom neurosurgery was performed for cerebellar vermis medulloblastoma in April 2000. After resection the patient underwent chemotherapy followed by radiotherapy, receiving 53.07 Gy to posterior fossa and 35.07 Gy to the rest of the craniospinal axis....
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2019-03-01
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| Series: | Folia Neuropathologica |
| Subjects: | |
| Online Access: | https://www.termedia.pl/Radiation-induced-anaplastic-astrocytoma-following-treatment-of-medulloblastoma,20,36148,1,1.html |
| _version_ | 1819237324609814528 |
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| author | Anna Mucha-Małecka Dominika Wojton-Dziewonska Dariusz Adamek Konrad Urbanek Krzysztof Małecki |
| author_facet | Anna Mucha-Małecka Dominika Wojton-Dziewonska Dariusz Adamek Konrad Urbanek Krzysztof Małecki |
| author_sort | Anna Mucha-Małecka |
| collection | DOAJ |
| description | We hereby report a case of a 10-year-old girl in whom neurosurgery was performed for cerebellar vermis medulloblastoma in April 2000. After resection the patient underwent chemotherapy followed by radiotherapy, receiving 53.07 Gy to posterior fossa and 35.07 Gy to the rest of the craniospinal axis. In 2012, she was diagnosed with anaplastic astrocytoma, which was located within the high-dose region. Surgical resection of the tumour was performed. Postoperatively, the patient received radiation therapy (50.4 Gy) with concurrent temozolomide, followed by 6 cycles of adjuvant temozolomide. Five years after the diagnosis of anaplastic astrocytoma, the patient remains asymptomatic. |
| first_indexed | 2024-12-23T13:18:31Z |
| format | Article |
| id | doaj.art-0ed0c21024cb498985ea8b3c96f1fe29 |
| institution | Directory Open Access Journal |
| issn | 1641-4640 1509-572X |
| language | English |
| last_indexed | 2024-12-23T13:18:31Z |
| publishDate | 2019-03-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Folia Neuropathologica |
| spelling | doaj.art-0ed0c21024cb498985ea8b3c96f1fe292022-12-21T17:45:31ZengTermedia Publishing HouseFolia Neuropathologica1641-46401509-572X2019-03-01571808610.5114/fn.2019.8383436148Radiation-induced anaplastic astrocytoma following treatment of medulloblastomaAnna Mucha-MałeckaDominika Wojton-DziewonskaDariusz AdamekKonrad UrbanekKrzysztof MałeckiWe hereby report a case of a 10-year-old girl in whom neurosurgery was performed for cerebellar vermis medulloblastoma in April 2000. After resection the patient underwent chemotherapy followed by radiotherapy, receiving 53.07 Gy to posterior fossa and 35.07 Gy to the rest of the craniospinal axis. In 2012, she was diagnosed with anaplastic astrocytoma, which was located within the high-dose region. Surgical resection of the tumour was performed. Postoperatively, the patient received radiation therapy (50.4 Gy) with concurrent temozolomide, followed by 6 cycles of adjuvant temozolomide. Five years after the diagnosis of anaplastic astrocytoma, the patient remains asymptomatic.https://www.termedia.pl/Radiation-induced-anaplastic-astrocytoma-following-treatment-of-medulloblastoma,20,36148,1,1.htmlmedulloblastoma anaplastic astrocytoma radiation-induced tumour chemoradiotherapy reirradiation |
| spellingShingle | Anna Mucha-Małecka Dominika Wojton-Dziewonska Dariusz Adamek Konrad Urbanek Krzysztof Małecki Radiation-induced anaplastic astrocytoma following treatment of medulloblastoma Folia Neuropathologica medulloblastoma anaplastic astrocytoma radiation-induced tumour chemoradiotherapy reirradiation |
| title | Radiation-induced anaplastic astrocytoma following treatment of medulloblastoma |
| title_full | Radiation-induced anaplastic astrocytoma following treatment of medulloblastoma |
| title_fullStr | Radiation-induced anaplastic astrocytoma following treatment of medulloblastoma |
| title_full_unstemmed | Radiation-induced anaplastic astrocytoma following treatment of medulloblastoma |
| title_short | Radiation-induced anaplastic astrocytoma following treatment of medulloblastoma |
| title_sort | radiation induced anaplastic astrocytoma following treatment of medulloblastoma |
| topic | medulloblastoma anaplastic astrocytoma radiation-induced tumour chemoradiotherapy reirradiation |
| url | https://www.termedia.pl/Radiation-induced-anaplastic-astrocytoma-following-treatment-of-medulloblastoma,20,36148,1,1.html |
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