Difficulties in diagnosing antibiotic-associated diarrhea using a clinical case example
Aim. To identify challenges in the diagnosis and treatment of a patient with intestinal damage due to long-term use of antibiotics. Material and methods. The case of antibiotic-associated diarrhea in a 65-year-old patient is described and analyzed. Results. The patient with a combined patholog...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Zaporozhye State Medical University
2023-10-01
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| Series: | Zaporožskij Medicinskij Žurnal |
| Subjects: | |
| Online Access: | http://zmj.zsmu.edu.ua/article/view/283350/282139 |
| _version_ | 1797653529421152256 |
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| author | V. I. Kryvenko I. S. Kachan O. P. Fedorova A. V. Kechejieva S. P. Pachomova |
| author_facet | V. I. Kryvenko I. S. Kachan O. P. Fedorova A. V. Kechejieva S. P. Pachomova |
| author_sort | V. I. Kryvenko |
| collection | DOAJ |
| description | Aim. To identify challenges in the diagnosis and treatment of a patient with intestinal damage due to long-term use of antibiotics.
Material and methods. The case of antibiotic-associated diarrhea in a 65-year-old patient is described and analyzed.
Results. The patient with a combined pathology of the gastrointestinal tract and cancer of the sigmoid colon developed a complication after a splenectomy – antibiotic-associated diarrhea. The clinical picture of diarrhea was complicated by the development of pseudomembranous colitis, which was masked by a leukemoid reaction and a septic process. The patient with the relapsing disease course developed multiple organ failure that resulted in a lethal outcome.
Conclusions. Diarrhea associated with Clostridia difficile caused the development of pseudomembranous colitis. At the same time, the clinical picture of the disease had a mask of a leukemoid reaction and a septic process. |
| first_indexed | 2024-03-11T16:44:54Z |
| format | Article |
| id | doaj.art-0ed2ccfe46ef43668eb9ece3d5dbce14 |
| institution | Directory Open Access Journal |
| issn | 2306-4145 2310-1210 |
| language | English |
| last_indexed | 2024-03-11T16:44:54Z |
| publishDate | 2023-10-01 |
| publisher | Zaporozhye State Medical University |
| record_format | Article |
| series | Zaporožskij Medicinskij Žurnal |
| spelling | doaj.art-0ed2ccfe46ef43668eb9ece3d5dbce142023-10-22T16:49:27ZengZaporozhye State Medical UniversityZaporožskij Medicinskij Žurnal2306-41452310-12102023-10-0125547247610.14739/2310-1210.2023.5.283350Difficulties in diagnosing antibiotic-associated diarrhea using a clinical case exampleV. I. Kryvenko0https://orcid.org/0000-0002-2050-3954I. S. Kachan1https://orcid.org/0000-0001-9249-7824O. P. Fedorova2https://orcid.org/0000-0003-3573-4234A. V. Kechejieva3S. P. Pachomova4https://orcid.org/0000-0002-8192-463XZaporizhzhia State Medical and Pharmaceutical University, UkraineZaporizhzhia State Medical and Pharmaceutical University, UkraineZaporizhzhia State Medical and Pharmaceutical University, UkraineSI “Territorial Medical Association of the Ministry of Internal Affairs of Ukraine in the Zaporizhzhia regionZaporizhzhia State Medical and Pharmaceutical University, UkraineAim. To identify challenges in the diagnosis and treatment of a patient with intestinal damage due to long-term use of antibiotics. Material and methods. The case of antibiotic-associated diarrhea in a 65-year-old patient is described and analyzed. Results. The patient with a combined pathology of the gastrointestinal tract and cancer of the sigmoid colon developed a complication after a splenectomy – antibiotic-associated diarrhea. The clinical picture of diarrhea was complicated by the development of pseudomembranous colitis, which was masked by a leukemoid reaction and a septic process. The patient with the relapsing disease course developed multiple organ failure that resulted in a lethal outcome. Conclusions. Diarrhea associated with Clostridia difficile caused the development of pseudomembranous colitis. At the same time, the clinical picture of the disease had a mask of a leukemoid reaction and a septic process.http://zmj.zsmu.edu.ua/article/view/283350/282139diarrheapseudomembranous colitisdiagnosistreatment |
| spellingShingle | V. I. Kryvenko I. S. Kachan O. P. Fedorova A. V. Kechejieva S. P. Pachomova Difficulties in diagnosing antibiotic-associated diarrhea using a clinical case example Zaporožskij Medicinskij Žurnal diarrhea pseudomembranous colitis diagnosis treatment |
| title | Difficulties in diagnosing antibiotic-associated diarrhea using a clinical case example |
| title_full | Difficulties in diagnosing antibiotic-associated diarrhea using a clinical case example |
| title_fullStr | Difficulties in diagnosing antibiotic-associated diarrhea using a clinical case example |
| title_full_unstemmed | Difficulties in diagnosing antibiotic-associated diarrhea using a clinical case example |
| title_short | Difficulties in diagnosing antibiotic-associated diarrhea using a clinical case example |
| title_sort | difficulties in diagnosing antibiotic associated diarrhea using a clinical case example |
| topic | diarrhea pseudomembranous colitis diagnosis treatment |
| url | http://zmj.zsmu.edu.ua/article/view/283350/282139 |
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