Using Akaike's information theoretic criterion in mixed-effects modeling of pharmacokinetic data: a simulation study [version 3; referees: 2 approved, 1 approved with reservations]
Akaike's information theoretic criterion for model discrimination (AIC) is often stated to "overfit", i.e., it selects models with a higher dimension than the dimension of the model that generated the data. However, with experimental pharmacokinetic data it may not be possible to iden...
Main Authors: | Erik Olofsen, Albert Dahan |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2015-07-01
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Series: | F1000Research |
Subjects: | |
Online Access: | http://f1000research.com/articles/2-71/v3 |
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