CRISPR/Cas9 Induced Somatic Recombination at the <i>CRTISO</i> Locus in Tomato

CRISPR/Cas9 Induced Somatic Recombination at the <i>CRTISO</i> Locus in Tomato

Homologous recombination (HR) in somatic cells is not as well understood as meiotic recombination and is thought to be rare. In a previous study, we showed that Inter-Homologous Somatic Recombination (IHSR) can be achieved by targeted induction of DNA double-strand breaks (DSBs). Here, we designed a...

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Bibliographic Details
Main Authors: Ilan Ben Shlush, Aviva Samach, Cathy Melamed-Bessudo, Daniela Ben-Tov, Tal Dahan-Meir, Shdema Filler-Hayut, Avraham A. Levy
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Genes
Subjects:
DNA double-strand break repair
homologous recombination
CRISPR/Cas9
inter homologous somatic recombination
targeted gene conversion
targeted crossover
Online Access:https://www.mdpi.com/2073-4425/12/1/59

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