Incidence of psychiatric illness among COVID-19-positive individuals with and without loss of smell or taste symptoms in a Tertiary Care Hospital in South India – A prospective cohort study
Background: COVID infection is known to cause acute and long-term neuropsychiatric presentations. Coronavirus infections are known to have neuroinvasive potential with consequent neuropsychiatric manifestations. Materials and Methods: The study was conducted in a tertiary care hospital, and COVID-19...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2022-01-01
|
| Series: | Annals of Indian Psychiatry |
| Subjects: | |
| Online Access: | http://www.anip.co.in/article.asp?issn=2588-8358;year=2022;volume=6;issue=2;spage=169;epage=175;aulast=Shankar |
| _version_ | 1798037563154366464 |
|---|---|
| author | S Shankar M Mohamed Ilyas Rahamathulla |
| author_facet | S Shankar M Mohamed Ilyas Rahamathulla |
| author_sort | S Shankar |
| collection | DOAJ |
| description | Background: COVID infection is known to cause acute and long-term neuropsychiatric presentations. Coronavirus infections are known to have neuroinvasive potential with consequent neuropsychiatric manifestations. Materials and Methods: The study was conducted in a tertiary care hospital, and COVID-19-positive individuals were grouped based on the presence or absence of loss of smell (anosmia) or taste symptoms (ageusia). Group 1 without smell or taste disturbance, and Group 2 with smell or taste disturbance. Both groups were followed up for 6 months to assess the new onset of psychiatric illness. Results: The onset of new psychiatric illness was present in 8 out of 30 (26.66%) cases in group 2 when compared with 2 out of 30 (6.66%) cases in Group 1, with a relative risk of 4 (95% confidence interval 0.9247–17.3023). In 10 cases, the pattern of psychiatric illness was depression (16.66%), anxiety (6.6%), posttraumatic stress disorder (3.33%), acute psychosis (3.33%), and acute stress disorder (3.33%). Both groups were compared in terms of socio-demographic profile, inflammatory markers, and computed tomography severity score, and no significant difference was noted between the two. A relative risk of 4 indicates that COVID-19-infected individuals who lose their sense of smell or taste are more likely to develop new-onset psychiatric illness. Conclusion: Impact of COVID-19 on the central nervous system is very evident, and loss of smell or taste symptoms could be an early marker. Early recognition and prompt treatment with immunotherapy or newer therapies will prevent the emergence of psychiatric disturbance and its disability. |
| first_indexed | 2024-04-11T21:28:14Z |
| format | Article |
| id | doaj.art-0edf4a93b3e546bc8546ce19c7c184bc |
| institution | Directory Open Access Journal |
| issn | 2588-8358 2588-8366 |
| language | English |
| last_indexed | 2024-04-11T21:28:14Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Indian Psychiatry |
| spelling | doaj.art-0edf4a93b3e546bc8546ce19c7c184bc2022-12-22T04:02:18ZengWolters Kluwer Medknow PublicationsAnnals of Indian Psychiatry2588-83582588-83662022-01-016216917510.4103/aip.aip_39_22Incidence of psychiatric illness among COVID-19-positive individuals with and without loss of smell or taste symptoms in a Tertiary Care Hospital in South India – A prospective cohort studyS ShankarM Mohamed Ilyas RahamathullaBackground: COVID infection is known to cause acute and long-term neuropsychiatric presentations. Coronavirus infections are known to have neuroinvasive potential with consequent neuropsychiatric manifestations. Materials and Methods: The study was conducted in a tertiary care hospital, and COVID-19-positive individuals were grouped based on the presence or absence of loss of smell (anosmia) or taste symptoms (ageusia). Group 1 without smell or taste disturbance, and Group 2 with smell or taste disturbance. Both groups were followed up for 6 months to assess the new onset of psychiatric illness. Results: The onset of new psychiatric illness was present in 8 out of 30 (26.66%) cases in group 2 when compared with 2 out of 30 (6.66%) cases in Group 1, with a relative risk of 4 (95% confidence interval 0.9247–17.3023). In 10 cases, the pattern of psychiatric illness was depression (16.66%), anxiety (6.6%), posttraumatic stress disorder (3.33%), acute psychosis (3.33%), and acute stress disorder (3.33%). Both groups were compared in terms of socio-demographic profile, inflammatory markers, and computed tomography severity score, and no significant difference was noted between the two. A relative risk of 4 indicates that COVID-19-infected individuals who lose their sense of smell or taste are more likely to develop new-onset psychiatric illness. Conclusion: Impact of COVID-19 on the central nervous system is very evident, and loss of smell or taste symptoms could be an early marker. Early recognition and prompt treatment with immunotherapy or newer therapies will prevent the emergence of psychiatric disturbance and its disability.http://www.anip.co.in/article.asp?issn=2588-8358;year=2022;volume=6;issue=2;spage=169;epage=175;aulast=Shankaranosmiaageusiacovid-19 infectionnew-onset psychiatric illness |
| spellingShingle | S Shankar M Mohamed Ilyas Rahamathulla Incidence of psychiatric illness among COVID-19-positive individuals with and without loss of smell or taste symptoms in a Tertiary Care Hospital in South India – A prospective cohort study Annals of Indian Psychiatry anosmia ageusia covid-19 infection new-onset psychiatric illness |
| title | Incidence of psychiatric illness among COVID-19-positive individuals with and without loss of smell or taste symptoms in a Tertiary Care Hospital in South India – A prospective cohort study |
| title_full | Incidence of psychiatric illness among COVID-19-positive individuals with and without loss of smell or taste symptoms in a Tertiary Care Hospital in South India – A prospective cohort study |
| title_fullStr | Incidence of psychiatric illness among COVID-19-positive individuals with and without loss of smell or taste symptoms in a Tertiary Care Hospital in South India – A prospective cohort study |
| title_full_unstemmed | Incidence of psychiatric illness among COVID-19-positive individuals with and without loss of smell or taste symptoms in a Tertiary Care Hospital in South India – A prospective cohort study |
| title_short | Incidence of psychiatric illness among COVID-19-positive individuals with and without loss of smell or taste symptoms in a Tertiary Care Hospital in South India – A prospective cohort study |
| title_sort | incidence of psychiatric illness among covid 19 positive individuals with and without loss of smell or taste symptoms in a tertiary care hospital in south india a prospective cohort study |
| topic | anosmia ageusia covid-19 infection new-onset psychiatric illness |
| url | http://www.anip.co.in/article.asp?issn=2588-8358;year=2022;volume=6;issue=2;spage=169;epage=175;aulast=Shankar |
| work_keys_str_mv | AT sshankar incidenceofpsychiatricillnessamongcovid19positiveindividualswithandwithoutlossofsmellortastesymptomsinatertiarycarehospitalinsouthindiaaprospectivecohortstudy AT mmohamedilyasrahamathulla incidenceofpsychiatricillnessamongcovid19positiveindividualswithandwithoutlossofsmellortastesymptomsinatertiarycarehospitalinsouthindiaaprospectivecohortstudy |