The Interventricular Septum: Structure, Function, Dysfunction, and Diseases
Vertebrates developed pulmonary circulation and septated the heart into venous and arterial compartments, as the adaptation from aquatic to terrestrial life requires more oxygen and energy. The interventricular septum (IVS) accommodates the ventricular portion of the conduction system and contribute...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/11/3227 |
| _version_ | 1797492804527587328 |
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| author | Filippos Triposkiadis Andrew Xanthopoulos Konstantinos Dean Boudoulas Grigorios Giamouzis Harisios Boudoulas John Skoularigis |
| author_facet | Filippos Triposkiadis Andrew Xanthopoulos Konstantinos Dean Boudoulas Grigorios Giamouzis Harisios Boudoulas John Skoularigis |
| author_sort | Filippos Triposkiadis |
| collection | DOAJ |
| description | Vertebrates developed pulmonary circulation and septated the heart into venous and arterial compartments, as the adaptation from aquatic to terrestrial life requires more oxygen and energy. The interventricular septum (IVS) accommodates the ventricular portion of the conduction system and contributes to the mechanical function of both ventricles. Conditions or diseases that affect IVS structure and function (e.g., hypertrophy, defects, other) may lead to ventricular pump failure and/or ventricular arrhythmias with grave consequences. IVS structure and function can be evaluated today using current imaging techniques. Effective therapies can be provided in most cases, although definitions of underlying etiologies may not always be easy, particularly in the elderly due to overlap between genetic and acquired causes of IVS hypertrophy, the most common being IVS abnormality. In this review, state-of-the-art information regarding IVS morphology, physiology, physiopathology, and disease is presented. |
| first_indexed | 2024-03-10T01:09:57Z |
| format | Article |
| id | doaj.art-0edf682872a24f4b88ce2b46ddb27d94 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T01:09:57Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-0edf682872a24f4b88ce2b46ddb27d942023-11-23T14:19:05ZengMDPI AGJournal of Clinical Medicine2077-03832022-06-011111322710.3390/jcm11113227The Interventricular Septum: Structure, Function, Dysfunction, and DiseasesFilippos Triposkiadis0Andrew Xanthopoulos1Konstantinos Dean Boudoulas2Grigorios Giamouzis3Harisios Boudoulas4John Skoularigis5Department of Cardiology, University Hospital of Larissa, 41110 Larissa, GreeceDepartment of Cardiology, University Hospital of Larissa, 41110 Larissa, GreeceDivision of Cardiovascular Medicine, The Ohio State University, Columbus, OH 43210, USADepartment of Cardiology, University Hospital of Larissa, 41110 Larissa, GreeceBiomedical Research Foundation, Academy of Athens, 11527 Athens, GreeceDepartment of Cardiology, University Hospital of Larissa, 41110 Larissa, GreeceVertebrates developed pulmonary circulation and septated the heart into venous and arterial compartments, as the adaptation from aquatic to terrestrial life requires more oxygen and energy. The interventricular septum (IVS) accommodates the ventricular portion of the conduction system and contributes to the mechanical function of both ventricles. Conditions or diseases that affect IVS structure and function (e.g., hypertrophy, defects, other) may lead to ventricular pump failure and/or ventricular arrhythmias with grave consequences. IVS structure and function can be evaluated today using current imaging techniques. Effective therapies can be provided in most cases, although definitions of underlying etiologies may not always be easy, particularly in the elderly due to overlap between genetic and acquired causes of IVS hypertrophy, the most common being IVS abnormality. In this review, state-of-the-art information regarding IVS morphology, physiology, physiopathology, and disease is presented.https://www.mdpi.com/2077-0383/11/11/3227interventricular septumstructurefunctiondiseasestreatment |
| spellingShingle | Filippos Triposkiadis Andrew Xanthopoulos Konstantinos Dean Boudoulas Grigorios Giamouzis Harisios Boudoulas John Skoularigis The Interventricular Septum: Structure, Function, Dysfunction, and Diseases Journal of Clinical Medicine interventricular septum structure function diseases treatment |
| title | The Interventricular Septum: Structure, Function, Dysfunction, and Diseases |
| title_full | The Interventricular Septum: Structure, Function, Dysfunction, and Diseases |
| title_fullStr | The Interventricular Septum: Structure, Function, Dysfunction, and Diseases |
| title_full_unstemmed | The Interventricular Septum: Structure, Function, Dysfunction, and Diseases |
| title_short | The Interventricular Septum: Structure, Function, Dysfunction, and Diseases |
| title_sort | interventricular septum structure function dysfunction and diseases |
| topic | interventricular septum structure function diseases treatment |
| url | https://www.mdpi.com/2077-0383/11/11/3227 |
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