Osteoblast-osteoclast co-cultures: A systematic review and map of available literature.

Drug research with animal models is expensive, time-consuming and translation to clinical trials is often poor, resulting in a desire to replace, reduce, and refine the use of animal models. One approach to replace and reduce the use of animal models is to use in vitro cell-culture models. To study...

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Bibliographic Details
Main Authors: Stefan J A Remmers, Bregje W M de Wildt, Michelle A M Vis, Eva S R Spaander, Rob B M de Vries, Keita Ito, Sandra Hofmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0257724