Opioid sparing strategies for perioperative pain management other than regional anaesthesia: A narrative review

Opioids play a crucial role in pain management in spite of causing increased hospital morbidity and related costs. It may also cause significant risks such as postoperative nausea and vomiting (PONV), sedation, sleep disturbances, urinary retention and respiratory depression (commonly referred to as...

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Main Authors: Babita Ghai, Anudeep Jafra, Nidhi Bhatia, Neha Chanana, Dipika Bansal, Vivek Mehta
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Journal of Anaesthesiology Clinical Pharmacology
Subjects:
Online Access:http://www.joacp.org/article.asp?issn=0970-9185;year=2022;volume=38;issue=1;spage=3;epage=10;aulast=Ghai
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author Babita Ghai
Anudeep Jafra
Nidhi Bhatia
Neha Chanana
Dipika Bansal
Vivek Mehta
author_facet Babita Ghai
Anudeep Jafra
Nidhi Bhatia
Neha Chanana
Dipika Bansal
Vivek Mehta
author_sort Babita Ghai
collection DOAJ
description Opioids play a crucial role in pain management in spite of causing increased hospital morbidity and related costs. It may also cause significant risks such as postoperative nausea and vomiting (PONV), sedation, sleep disturbances, urinary retention and respiratory depression (commonly referred to as opioid related adverse effects) in postoperative patients. In order to evade these opioid related side effects and also improve pain management, multimodal analgesia i.e., combination of different analgesics, was introduced more than a decade ago. Both pharmacological and non-pharmacological techniques are available as opioid sparing analgesia. Research from around the world have proved pharmacological techniques ranging from acetaminophen, NSAIDs (non-steroidal anti-inflammatory drugs), N-methyl-D-aspartate receptor antagonists (NDMA), alpha-2 agonists, anticonvulsants such as gamma aminobutyric acid analogues, beta-blockers, capsaicin, lignocaine infusion to glucocorticoids to be effective. On the other hand, non-pharmacological methods include techniques such as cognitive behavioral therapy, transcutaneous electrical nerve stimulation (TENS), electroanalgesia, acupuncture and hypnosis. However, research regarding the effect of these non-pharmacological techniques on pain management is still needed.
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spelling doaj.art-0ee27ade399a404fbe7a0695d6122af02022-12-22T00:32:57ZengWolters Kluwer Medknow PublicationsJournal of Anaesthesiology Clinical Pharmacology0970-91852022-01-0138131010.4103/joacp.JOACP_362_19Opioid sparing strategies for perioperative pain management other than regional anaesthesia: A narrative reviewBabita GhaiAnudeep JafraNidhi BhatiaNeha ChananaDipika BansalVivek MehtaOpioids play a crucial role in pain management in spite of causing increased hospital morbidity and related costs. It may also cause significant risks such as postoperative nausea and vomiting (PONV), sedation, sleep disturbances, urinary retention and respiratory depression (commonly referred to as opioid related adverse effects) in postoperative patients. In order to evade these opioid related side effects and also improve pain management, multimodal analgesia i.e., combination of different analgesics, was introduced more than a decade ago. Both pharmacological and non-pharmacological techniques are available as opioid sparing analgesia. Research from around the world have proved pharmacological techniques ranging from acetaminophen, NSAIDs (non-steroidal anti-inflammatory drugs), N-methyl-D-aspartate receptor antagonists (NDMA), alpha-2 agonists, anticonvulsants such as gamma aminobutyric acid analogues, beta-blockers, capsaicin, lignocaine infusion to glucocorticoids to be effective. On the other hand, non-pharmacological methods include techniques such as cognitive behavioral therapy, transcutaneous electrical nerve stimulation (TENS), electroanalgesia, acupuncture and hypnosis. However, research regarding the effect of these non-pharmacological techniques on pain management is still needed.http://www.joacp.org/article.asp?issn=0970-9185;year=2022;volume=38;issue=1;spage=3;epage=10;aulast=Ghaiacupuncturecognitive behavioral therapyenhanced recovery after surgerymultimodal analgesianon pharmacological therapiesopioid sparing strategiespharmacological techniquespostoperative pain
spellingShingle Babita Ghai
Anudeep Jafra
Nidhi Bhatia
Neha Chanana
Dipika Bansal
Vivek Mehta
Opioid sparing strategies for perioperative pain management other than regional anaesthesia: A narrative review
Journal of Anaesthesiology Clinical Pharmacology
acupuncture
cognitive behavioral therapy
enhanced recovery after surgery
multimodal analgesia
non pharmacological therapies
opioid sparing strategies
pharmacological techniques
postoperative pain
title Opioid sparing strategies for perioperative pain management other than regional anaesthesia: A narrative review
title_full Opioid sparing strategies for perioperative pain management other than regional anaesthesia: A narrative review
title_fullStr Opioid sparing strategies for perioperative pain management other than regional anaesthesia: A narrative review
title_full_unstemmed Opioid sparing strategies for perioperative pain management other than regional anaesthesia: A narrative review
title_short Opioid sparing strategies for perioperative pain management other than regional anaesthesia: A narrative review
title_sort opioid sparing strategies for perioperative pain management other than regional anaesthesia a narrative review
topic acupuncture
cognitive behavioral therapy
enhanced recovery after surgery
multimodal analgesia
non pharmacological therapies
opioid sparing strategies
pharmacological techniques
postoperative pain
url http://www.joacp.org/article.asp?issn=0970-9185;year=2022;volume=38;issue=1;spage=3;epage=10;aulast=Ghai
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AT nidhibhatia opioidsparingstrategiesforperioperativepainmanagementotherthanregionalanaesthesiaanarrativereview
AT nehachanana opioidsparingstrategiesforperioperativepainmanagementotherthanregionalanaesthesiaanarrativereview
AT dipikabansal opioidsparingstrategiesforperioperativepainmanagementotherthanregionalanaesthesiaanarrativereview
AT vivekmehta opioidsparingstrategiesforperioperativepainmanagementotherthanregionalanaesthesiaanarrativereview