Exploring the efficacy of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a natural compound in strengthening maize resistance against biotic and abiotic stressors: an empirical computational study
ObjectiveThis study aims to understand plant-bacteria interactions that enhance plant resistance to environmental stressors, with a focus on maize (Zea mays L.) and its vulnerability to various pathogenic organisms. We examine the potential of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a compo...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1232086/full |
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| author | Sandip Debnath Abdallah M. Elgorban Ali H. Bahkali Rajalakshmanan Eswaramoorthy Meenakshi Verma Pragya Tiwari Shifa Wang Ling Shing Wong Asad Syed |
| author_facet | Sandip Debnath Abdallah M. Elgorban Ali H. Bahkali Rajalakshmanan Eswaramoorthy Meenakshi Verma Pragya Tiwari Shifa Wang Ling Shing Wong Asad Syed |
| author_sort | Sandip Debnath |
| collection | DOAJ |
| description | ObjectiveThis study aims to understand plant-bacteria interactions that enhance plant resistance to environmental stressors, with a focus on maize (Zea mays L.) and its vulnerability to various pathogenic organisms. We examine the potential of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a compound to boost maize’s resilience against stressors and pathogens.BackgroundWith the growing global population and increased food demand, the study of endophytes, comprising bacteria and fungi, becomes crucial. They reside within plant tissues, affecting their hosts either beneficially or detrimentally. Agrobacteria are of specific interest due to their potential to contribute to developing strategies for plant resistance enhancement.MethodsWe conducted exhaustive research on the defense-related proteins and mechanisms involved in maize-pathogen interactions. The efficacy of ACCA as a natural-compound that could enhance maize’s resistance was examined.ResultsOur research indicates that ACCA, having a binding energy of −9.98 kcal/mol, successfully strengthens maize resistance against pathogenic assaults and drought stress. It plays a crucial protective role in maize plants as they mature, outperforming other ligands in its effectiveness to improve productivity and increase yield.ConclusionApplying ACCA to maize plants has considerable potential in enhancing their resilience and tolerance to stress, proving to be an effective strategy to boost crop yield and productivity. This could help address the increasing global food demand. However, more research is needed to optimize ACCA application methods and to gain a comprehensive understanding of its long-term effects on maize cultivations and the environment. |
| first_indexed | 2024-03-12T15:08:52Z |
| format | Article |
| id | doaj.art-0ee4c609cfd04f5d8d901404fc5b386b |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-03-12T15:08:52Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-0ee4c609cfd04f5d8d901404fc5b386b2023-08-11T23:06:51ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2023-08-011410.3389/fmicb.2023.12320861232086Exploring the efficacy of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a natural compound in strengthening maize resistance against biotic and abiotic stressors: an empirical computational studySandip Debnath0Abdallah M. Elgorban1Ali H. Bahkali2Rajalakshmanan Eswaramoorthy3Meenakshi Verma4Pragya Tiwari5Shifa Wang6Ling Shing Wong7Asad Syed8Department of Genetics and Plant Breeding, Institute of Agriculture, Visva-Bharati University, Sriniketan, IndiaDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi ArabiaDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi ArabiaDepartment of Biochemistry, Centre of Molecular Medicine and Diagnostics (COMMAND), Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, IndiaUniversity Centre for Research and Development, Department of Chemistry, Chandigarh University, Gharuan, Mohali, IndiaDepartment of Biotechnology, Yeungnam University, Gyeongsan, Republic of KoreaSchool of Electronic and Information Engineering, Chongqing Three Gorges University, Chongqing, ChinaFaculty of Health and Life Sciences, INTI International University, Nilai, MalaysiaDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi ArabiaObjectiveThis study aims to understand plant-bacteria interactions that enhance plant resistance to environmental stressors, with a focus on maize (Zea mays L.) and its vulnerability to various pathogenic organisms. We examine the potential of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a compound to boost maize’s resilience against stressors and pathogens.BackgroundWith the growing global population and increased food demand, the study of endophytes, comprising bacteria and fungi, becomes crucial. They reside within plant tissues, affecting their hosts either beneficially or detrimentally. Agrobacteria are of specific interest due to their potential to contribute to developing strategies for plant resistance enhancement.MethodsWe conducted exhaustive research on the defense-related proteins and mechanisms involved in maize-pathogen interactions. The efficacy of ACCA as a natural-compound that could enhance maize’s resistance was examined.ResultsOur research indicates that ACCA, having a binding energy of −9.98 kcal/mol, successfully strengthens maize resistance against pathogenic assaults and drought stress. It plays a crucial protective role in maize plants as they mature, outperforming other ligands in its effectiveness to improve productivity and increase yield.ConclusionApplying ACCA to maize plants has considerable potential in enhancing their resilience and tolerance to stress, proving to be an effective strategy to boost crop yield and productivity. This could help address the increasing global food demand. However, more research is needed to optimize ACCA application methods and to gain a comprehensive understanding of its long-term effects on maize cultivations and the environment.https://www.frontiersin.org/articles/10.3389/fmicb.2023.1232086/full1-amino-cyclopropane-1-carboxylic aciddrought resistancefungal attackmicrobial attackmolecular dockingmolecular dynamics |
| spellingShingle | Sandip Debnath Abdallah M. Elgorban Ali H. Bahkali Rajalakshmanan Eswaramoorthy Meenakshi Verma Pragya Tiwari Shifa Wang Ling Shing Wong Asad Syed Exploring the efficacy of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a natural compound in strengthening maize resistance against biotic and abiotic stressors: an empirical computational study Frontiers in Microbiology 1-amino-cyclopropane-1-carboxylic acid drought resistance fungal attack microbial attack molecular docking molecular dynamics |
| title | Exploring the efficacy of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a natural compound in strengthening maize resistance against biotic and abiotic stressors: an empirical computational study |
| title_full | Exploring the efficacy of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a natural compound in strengthening maize resistance against biotic and abiotic stressors: an empirical computational study |
| title_fullStr | Exploring the efficacy of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a natural compound in strengthening maize resistance against biotic and abiotic stressors: an empirical computational study |
| title_full_unstemmed | Exploring the efficacy of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a natural compound in strengthening maize resistance against biotic and abiotic stressors: an empirical computational study |
| title_short | Exploring the efficacy of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a natural compound in strengthening maize resistance against biotic and abiotic stressors: an empirical computational study |
| title_sort | exploring the efficacy of 1 amino cyclopropane 1 carboxylic acid acca as a natural compound in strengthening maize resistance against biotic and abiotic stressors an empirical computational study |
| topic | 1-amino-cyclopropane-1-carboxylic acid drought resistance fungal attack microbial attack molecular docking molecular dynamics |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1232086/full |
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