Effects of transfusion load and suction pressure on renal function in intraoperative salvage autotransfusion
Although some investigations have been performed to determine the effects of transfusion load and suction pressure on renal function during intraoperative salvage autotransfusion, the precise threshold is still undetermined. A total of 625 patients undergoing surgery with the Continuous AutoTransfus...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Associação Brasileira de Divulgação Científica
2021-01-01
|
| Series: | Brazilian Journal of Medical and Biological Research |
| Subjects: | |
| Online Access: | http://www.scielo.br/pdf/bjmbr/v54n3/1414-431X-bjmbr-54-3-e10292.pdf |
| _version_ | 1819098128998989824 |
|---|---|
| author | Jingyang Zeng Sijie Zhang Qilin Wu Shunyuan Li Yingle Chen Biyu Wu |
| author_facet | Jingyang Zeng Sijie Zhang Qilin Wu Shunyuan Li Yingle Chen Biyu Wu |
| author_sort | Jingyang Zeng |
| collection | DOAJ |
| description | Although some investigations have been performed to determine the effects of transfusion load and suction pressure on renal function during intraoperative salvage autotransfusion, the precise threshold is still undetermined. A total of 625 patients undergoing surgery with the Continuous AutoTransfusion System (CATSplus) were enrolled and divided into groups according to the utilized suction pressure and transfusion volume. Plasma free hemoglobin (FHB) and creatinine clearance (CCr) were assayed to indicate the renal function. Both 0.03 MPa suction (≥4-unit load) and >5 units transfusion changed the levels of FHB and CCr significantly when measured 24 h post-operation compared to pre-operation. Under 0.02 MPa suction (≥4-unit load), the alteration of FHB and CCr returned to normal after 24 h. Under 3 units transfusion, the levels of FHB and CCr at 6 and 12 h post-operation changed significantly compared to pre-operation (P<0.05 or P<0.01, respectively), and this alteration could be restored to normal at 72 h post-operation. After an exhaustive investigation, less than 4 units transfusion and less than 0.03 MPa suction pressure are recommended for intraoperative salvage autotransfusion. |
| first_indexed | 2024-12-22T00:26:04Z |
| format | Article |
| id | doaj.art-0ee661bbbead43dbb98bd535a9438bb7 |
| institution | Directory Open Access Journal |
| issn | 1414-431X |
| language | English |
| last_indexed | 2024-12-22T00:26:04Z |
| publishDate | 2021-01-01 |
| publisher | Associação Brasileira de Divulgação Científica |
| record_format | Article |
| series | Brazilian Journal of Medical and Biological Research |
| spelling | doaj.art-0ee661bbbead43dbb98bd535a9438bb72022-12-21T18:45:03ZengAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research1414-431X2021-01-0154310.1590/1414-431x202010292Effects of transfusion load and suction pressure on renal function in intraoperative salvage autotransfusionJingyang Zenghttps://orcid.org/0000-0002-6523-505XSijie Zhanghttps://orcid.org/0000-0003-0659-6127Qilin Wuhttps://orcid.org/0000-0003-2668-4722Shunyuan Lihttps://orcid.org/0000-0003-1778-8386Yingle Chenhttps://orcid.org/0000-0002-8742-7271Biyu Wuhttps://orcid.org/0000-0002-1421-6967Although some investigations have been performed to determine the effects of transfusion load and suction pressure on renal function during intraoperative salvage autotransfusion, the precise threshold is still undetermined. A total of 625 patients undergoing surgery with the Continuous AutoTransfusion System (CATSplus) were enrolled and divided into groups according to the utilized suction pressure and transfusion volume. Plasma free hemoglobin (FHB) and creatinine clearance (CCr) were assayed to indicate the renal function. Both 0.03 MPa suction (≥4-unit load) and >5 units transfusion changed the levels of FHB and CCr significantly when measured 24 h post-operation compared to pre-operation. Under 0.02 MPa suction (≥4-unit load), the alteration of FHB and CCr returned to normal after 24 h. Under 3 units transfusion, the levels of FHB and CCr at 6 and 12 h post-operation changed significantly compared to pre-operation (P<0.05 or P<0.01, respectively), and this alteration could be restored to normal at 72 h post-operation. After an exhaustive investigation, less than 4 units transfusion and less than 0.03 MPa suction pressure are recommended for intraoperative salvage autotransfusion.http://www.scielo.br/pdf/bjmbr/v54n3/1414-431X-bjmbr-54-3-e10292.pdfIntraoperative salvage autotransfusionPlasma-free hemoglobinCreatinine clearance |
| spellingShingle | Jingyang Zeng Sijie Zhang Qilin Wu Shunyuan Li Yingle Chen Biyu Wu Effects of transfusion load and suction pressure on renal function in intraoperative salvage autotransfusion Brazilian Journal of Medical and Biological Research Intraoperative salvage autotransfusion Plasma-free hemoglobin Creatinine clearance |
| title | Effects of transfusion load and suction pressure on renal function in intraoperative salvage autotransfusion |
| title_full | Effects of transfusion load and suction pressure on renal function in intraoperative salvage autotransfusion |
| title_fullStr | Effects of transfusion load and suction pressure on renal function in intraoperative salvage autotransfusion |
| title_full_unstemmed | Effects of transfusion load and suction pressure on renal function in intraoperative salvage autotransfusion |
| title_short | Effects of transfusion load and suction pressure on renal function in intraoperative salvage autotransfusion |
| title_sort | effects of transfusion load and suction pressure on renal function in intraoperative salvage autotransfusion |
| topic | Intraoperative salvage autotransfusion Plasma-free hemoglobin Creatinine clearance |
| url | http://www.scielo.br/pdf/bjmbr/v54n3/1414-431X-bjmbr-54-3-e10292.pdf |
| work_keys_str_mv | AT jingyangzeng effectsoftransfusionloadandsuctionpressureonrenalfunctioninintraoperativesalvageautotransfusion AT sijiezhang effectsoftransfusionloadandsuctionpressureonrenalfunctioninintraoperativesalvageautotransfusion AT qilinwu effectsoftransfusionloadandsuctionpressureonrenalfunctioninintraoperativesalvageautotransfusion AT shunyuanli effectsoftransfusionloadandsuctionpressureonrenalfunctioninintraoperativesalvageautotransfusion AT yinglechen effectsoftransfusionloadandsuctionpressureonrenalfunctioninintraoperativesalvageautotransfusion AT biyuwu effectsoftransfusionloadandsuctionpressureonrenalfunctioninintraoperativesalvageautotransfusion |