In Vitro and In Silico Analysis of New n-Butyl and Isobutyl Quinoxaline-7-carboxylate 1,4-di-<i>N</i>-oxide Derivatives against <i>Trypanosoma cruzi</i> as Trypanothione Reductase Inhibitors
American trypanosomiasis is a worldwide health problem that requires attention due to ineffective treatment options. We evaluated n-butyl and isobutyl quinoxaline-7-carboxylate 1,4-di-<i>N</i>-oxide derivatives against trypomastigotes of the <i>Trypanosoma cruzi</i> strains N...
Main Authors: | Alonzo González-González, Oscar Sánchez-Sánchez, R. Luise Krauth-Siegel, Maria Laura Bolognesi, Rogelio Gớmez-Escobedo, Benjamín Nogueda-Torres, Lenci K. Vázquez-Jiménez, Emma Saavedra, Rusely Encalada, José Carlos Espinoza-Hicks, Alma D. Paz-González, Gildardo Rivera |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/21/13315 |
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