Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration
The knowledge about how different subsystems participate and interplay in sensorimotor control is fundamental to understand motor deficits associated with CNS injury and movement recovery. The role of corticospinal (CS) and rubrospinal (RS) projections in motor control has been extensively studied a...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-06-01
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| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2021.686481/full |
| _version_ | 1818588448494190592 |
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| author | Rafael Olivares-Moreno Paola Rodriguez-Moreno Veronica Lopez-Virgen Martín Macías Moisés Altamira-Camacho Gerardo Rojas-Piloni |
| author_facet | Rafael Olivares-Moreno Paola Rodriguez-Moreno Veronica Lopez-Virgen Martín Macías Moisés Altamira-Camacho Gerardo Rojas-Piloni |
| author_sort | Rafael Olivares-Moreno |
| collection | DOAJ |
| description | The knowledge about how different subsystems participate and interplay in sensorimotor control is fundamental to understand motor deficits associated with CNS injury and movement recovery. The role of corticospinal (CS) and rubrospinal (RS) projections in motor control has been extensively studied and compared, and it is clear that both systems are important for skilled movement. However, during phylogeny, the emerging cerebral cortex took a higher hierarchical role controlling rubro-cerebellar circuits. Here, we present anatomical, neurophysiological, and behavioral evidence suggesting that both systems modulate complex segmental neuronal networks in a parallel way, which is important for sensorimotor integration at spinal cord level. We also highlight that, although specializations exist, both systems could be complementary and potentially subserve motor recovery associated with CNS damage. |
| first_indexed | 2024-12-16T09:24:55Z |
| format | Article |
| id | doaj.art-0ee844a7c8e249dd825e0c3b2a732e8c |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-12-16T09:24:55Z |
| publishDate | 2021-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-0ee844a7c8e249dd825e0c3b2a732e8c2022-12-21T22:36:40ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2021-06-011510.3389/fnins.2021.686481686481Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor IntegrationRafael Olivares-MorenoPaola Rodriguez-MorenoVeronica Lopez-VirgenMartín MacíasMoisés Altamira-CamachoGerardo Rojas-PiloniThe knowledge about how different subsystems participate and interplay in sensorimotor control is fundamental to understand motor deficits associated with CNS injury and movement recovery. The role of corticospinal (CS) and rubrospinal (RS) projections in motor control has been extensively studied and compared, and it is clear that both systems are important for skilled movement. However, during phylogeny, the emerging cerebral cortex took a higher hierarchical role controlling rubro-cerebellar circuits. Here, we present anatomical, neurophysiological, and behavioral evidence suggesting that both systems modulate complex segmental neuronal networks in a parallel way, which is important for sensorimotor integration at spinal cord level. We also highlight that, although specializations exist, both systems could be complementary and potentially subserve motor recovery associated with CNS damage.https://www.frontiersin.org/articles/10.3389/fnins.2021.686481/fullmotor controlmotor cortexred nucleusspinal cordmotor recovery |
| spellingShingle | Rafael Olivares-Moreno Paola Rodriguez-Moreno Veronica Lopez-Virgen Martín Macías Moisés Altamira-Camacho Gerardo Rojas-Piloni Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration Frontiers in Neuroscience motor control motor cortex red nucleus spinal cord motor recovery |
| title | Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration |
| title_full | Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration |
| title_fullStr | Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration |
| title_full_unstemmed | Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration |
| title_short | Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration |
| title_sort | corticospinal vs rubrospinal revisited an evolutionary perspective for sensorimotor integration |
| topic | motor control motor cortex red nucleus spinal cord motor recovery |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2021.686481/full |
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