The Tetrahydrofuran Motif in Polyketide Marine Drugs
Oxygen heterocycles are units that are abundant in a great number of marine natural products. Among them, marine polyketides containing tetrahydrofuran rings have attracted great attention within the scientific community due to their challenging structures and promising biological activities. An ove...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Marine Drugs |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1660-3397/20/2/120 |
| _version_ | 1797478523107016704 |
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| author | Laura Fernández-Peña Carlos Díez-Poza Paula González-Andrés Asunción Barbero |
| author_facet | Laura Fernández-Peña Carlos Díez-Poza Paula González-Andrés Asunción Barbero |
| author_sort | Laura Fernández-Peña |
| collection | DOAJ |
| description | Oxygen heterocycles are units that are abundant in a great number of marine natural products. Among them, marine polyketides containing tetrahydrofuran rings have attracted great attention within the scientific community due to their challenging structures and promising biological activities. An overview of the most important marine tetrahydrofuran polyketides, with a focused discussion on their isolation, structure determination, approaches to their total synthesis, and biological studies is provided. |
| first_indexed | 2024-03-09T21:33:03Z |
| format | Article |
| id | doaj.art-0eead2ba4f1f4b87b6c73d84bba64886 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-03-09T21:33:03Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-0eead2ba4f1f4b87b6c73d84bba648862023-11-23T20:50:09ZengMDPI AGMarine Drugs1660-33972022-02-0120212010.3390/md20020120The Tetrahydrofuran Motif in Polyketide Marine DrugsLaura Fernández-Peña0Carlos Díez-Poza1Paula González-Andrés2Asunción Barbero3Department of Organic Chemistry, Campus Miguel Delibes, University of Valladolid, 47011 Valladolid, SpainDepartment of Organic Chemistry, Campus Miguel Delibes, University of Valladolid, 47011 Valladolid, SpainDepartment of Organic Chemistry, Campus Miguel Delibes, University of Valladolid, 47011 Valladolid, SpainDepartment of Organic Chemistry, Campus Miguel Delibes, University of Valladolid, 47011 Valladolid, SpainOxygen heterocycles are units that are abundant in a great number of marine natural products. Among them, marine polyketides containing tetrahydrofuran rings have attracted great attention within the scientific community due to their challenging structures and promising biological activities. An overview of the most important marine tetrahydrofuran polyketides, with a focused discussion on their isolation, structure determination, approaches to their total synthesis, and biological studies is provided.https://www.mdpi.com/1660-3397/20/2/120marine natural productsoxygen heterocyclestetrahydrofurantotal synthesisbiological activity |
| spellingShingle | Laura Fernández-Peña Carlos Díez-Poza Paula González-Andrés Asunción Barbero The Tetrahydrofuran Motif in Polyketide Marine Drugs Marine Drugs marine natural products oxygen heterocycles tetrahydrofuran total synthesis biological activity |
| title | The Tetrahydrofuran Motif in Polyketide Marine Drugs |
| title_full | The Tetrahydrofuran Motif in Polyketide Marine Drugs |
| title_fullStr | The Tetrahydrofuran Motif in Polyketide Marine Drugs |
| title_full_unstemmed | The Tetrahydrofuran Motif in Polyketide Marine Drugs |
| title_short | The Tetrahydrofuran Motif in Polyketide Marine Drugs |
| title_sort | tetrahydrofuran motif in polyketide marine drugs |
| topic | marine natural products oxygen heterocycles tetrahydrofuran total synthesis biological activity |
| url | https://www.mdpi.com/1660-3397/20/2/120 |
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