Oxoisoaporphine as Potent Telomerase Inhibitor

Two compounds previously isolated from traditional Chinese medicine, Menispermum dauricum (DC), 6-hydroxyl-oxoisoaporphine (H-La), and 4,6-di(2-pyridinyl)benzo[h]isoindolo[4,5,6-de]quinolin-8(5H)-one (H-Lb), were known to have in vitro antitumor activity and to selectively bind human telomeric, c-my...

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Hlavní autoři: Zu-Zhuang Wei, Qi-Pin Qin, Jia-Nian Chen, Zhen-Feng Chen
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2016-11-01
Edice:Molecules
Témata:
On-line přístup:http://www.mdpi.com/1420-3049/21/11/1534