Comprehensive Analysis Reveals USP45 as a Novel Putative Oncogene in Pan-Cancer

Comprehensive Analysis Reveals USP45 as a Novel Putative Oncogene in Pan-Cancer

Background: Deubiquitinating enzymes specifically removes ubiquitin molecules from ubiquitin-tagged target proteins, thereby inhibiting the degradation of target proteins and playing an important role in tumor. However, the mechanism of deubiquitinating enzyme USP45 in tumors remains unclear.Methods...

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Bibliographic Details
Main Authors: Kai Li, Qian Wang, Hua Bian, Zhiguo Chen, Haifa He, Xulin Zhao, Pengju Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
deubiquitinating enzyme
USP45
pan-cancer analysis
tumor immunotherapy
TCGA (The Cancer Genome Atlas Program)
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.886904/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2022.886904/full

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