A comparison of modelling techniques for computing wall stress in abdominal aortic aneurysms
<p>Abstract</p> <p>Background</p> <p>Aneurysms, in particular abdominal aortic aneurysms (AAA), form a significant portion of cardiovascular related deaths. There is much debate as to the most suitable tool for rupture prediction and interventional surgery of AAAs, and...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2007-10-01
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| Series: | BioMedical Engineering OnLine |
| Online Access: | http://www.biomedical-engineering-online.com/content/6/1/38 |
| _version_ | 1819121911643242496 |
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| author | McGloughlin Timothy M Callanan Anthony Doyle Barry J |
| author_facet | McGloughlin Timothy M Callanan Anthony Doyle Barry J |
| author_sort | McGloughlin Timothy M |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Aneurysms, in particular abdominal aortic aneurysms (AAA), form a significant portion of cardiovascular related deaths. There is much debate as to the most suitable tool for rupture prediction and interventional surgery of AAAs, and currently maximum diameter is used clinically as the determining factor for surgical intervention. Stress analysis techniques, such as finite element analysis (FEA) to compute the wall stress in patient-specific AAAs, have been regarded by some authors to be more clinically important than the use of a "one-size-fits-all" maximum diameter criterion, since some small AAAs have been shown to have higher wall stress than larger AAAs and have been known to rupture.</p> <p>Methods</p> <p>A patient-specific AAA was selected from our AAA database and 3D reconstruction was performed. The AAA was then modelled in this study using three different approaches, namely, <it>AAA</it>(<it>SIMP</it>), <it>AAA</it>(<it>MOD</it>) and <it>AAA</it>(<it>COMP</it>), with each model examined using linear and non-linear material properties. All models were analysed using the finite element method for wall stress distributions.</p> <p>Results</p> <p>Wall stress results show marked differences in peak wall stress results between the three methods. Peak wall stress was shown to reduce when more realistic parameters were utilised. It was also noted that wall stress was shown to reduce by 59% when modelled using the most accurate non-linear complex approach, compared to the same model without intraluminal thrombus.</p> <p>Conclusion</p> <p>The results here show that using more realistic parameters affect resulting wall stress. The use of simplified computational modelling methods can lead to inaccurate stress distributions. Care should be taken when examining stress results found using simplified techniques, in particular, if the wall stress results are to have clinical importance.</p> |
| first_indexed | 2024-12-22T06:44:05Z |
| format | Article |
| id | doaj.art-0ef44f93f053476eacc509c7c6612e58 |
| institution | Directory Open Access Journal |
| issn | 1475-925X |
| language | English |
| last_indexed | 2024-12-22T06:44:05Z |
| publishDate | 2007-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BioMedical Engineering OnLine |
| spelling | doaj.art-0ef44f93f053476eacc509c7c6612e582022-12-21T18:35:21ZengBMCBioMedical Engineering OnLine1475-925X2007-10-01613810.1186/1475-925X-6-38A comparison of modelling techniques for computing wall stress in abdominal aortic aneurysmsMcGloughlin Timothy MCallanan AnthonyDoyle Barry J<p>Abstract</p> <p>Background</p> <p>Aneurysms, in particular abdominal aortic aneurysms (AAA), form a significant portion of cardiovascular related deaths. There is much debate as to the most suitable tool for rupture prediction and interventional surgery of AAAs, and currently maximum diameter is used clinically as the determining factor for surgical intervention. Stress analysis techniques, such as finite element analysis (FEA) to compute the wall stress in patient-specific AAAs, have been regarded by some authors to be more clinically important than the use of a "one-size-fits-all" maximum diameter criterion, since some small AAAs have been shown to have higher wall stress than larger AAAs and have been known to rupture.</p> <p>Methods</p> <p>A patient-specific AAA was selected from our AAA database and 3D reconstruction was performed. The AAA was then modelled in this study using three different approaches, namely, <it>AAA</it>(<it>SIMP</it>), <it>AAA</it>(<it>MOD</it>) and <it>AAA</it>(<it>COMP</it>), with each model examined using linear and non-linear material properties. All models were analysed using the finite element method for wall stress distributions.</p> <p>Results</p> <p>Wall stress results show marked differences in peak wall stress results between the three methods. Peak wall stress was shown to reduce when more realistic parameters were utilised. It was also noted that wall stress was shown to reduce by 59% when modelled using the most accurate non-linear complex approach, compared to the same model without intraluminal thrombus.</p> <p>Conclusion</p> <p>The results here show that using more realistic parameters affect resulting wall stress. The use of simplified computational modelling methods can lead to inaccurate stress distributions. Care should be taken when examining stress results found using simplified techniques, in particular, if the wall stress results are to have clinical importance.</p>http://www.biomedical-engineering-online.com/content/6/1/38 |
| spellingShingle | McGloughlin Timothy M Callanan Anthony Doyle Barry J A comparison of modelling techniques for computing wall stress in abdominal aortic aneurysms BioMedical Engineering OnLine |
| title | A comparison of modelling techniques for computing wall stress in abdominal aortic aneurysms |
| title_full | A comparison of modelling techniques for computing wall stress in abdominal aortic aneurysms |
| title_fullStr | A comparison of modelling techniques for computing wall stress in abdominal aortic aneurysms |
| title_full_unstemmed | A comparison of modelling techniques for computing wall stress in abdominal aortic aneurysms |
| title_short | A comparison of modelling techniques for computing wall stress in abdominal aortic aneurysms |
| title_sort | comparison of modelling techniques for computing wall stress in abdominal aortic aneurysms |
| url | http://www.biomedical-engineering-online.com/content/6/1/38 |
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