Enzyme-linked immunosorbent assays using virus-like particles containing mutations of conserved residues on envelope protein can distinguish three flavivirus infections

Enzyme-linked immunosorbent assays using virus-like particles containing mutations of conserved residues on envelope protein can distinguish three flavivirus infections

ABSTRACTThe recent outbreaks of Zika virus (ZIKV) in flavivirus-endemic regions highlight the need for sensitive and specific serological tests. Previously we and others reported key fusion loop (FL) residues and/or BC loop (BCL) residues on dengue virus (DENV) envelope protein recognized by flavivi...

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Bibliographic Details
Main Authors: Wen-Yang Tsai, Kaitlin Driesse, Jih-Jin Tsai, Szu-Chia Hsieh, Robert Sznajder Granat, Olivia Jenkins, Gwong-Jen Chang, Wei-Kung Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
Zika virus
flavivirus
virus-like particles
serodiagnosis
fusion loop
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1797540

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