Clinical and radiographic study of the use of cross-linked gelfoam matrix in the treatment of dehiscence-like defects in Stage III periodontitis

Background: This clinical study aimed to overcome the difficulty of graft fixation and limited blood supply for dehiscence defects regeneration by using a cross-linked gelfoam matrix jointly with collagen membrane and xenograft. Materials and Methods: The study included twenty dehiscence-like defe...

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Main Authors: Mohamed Omar Elboraey, Sherouk Mohamed Gamal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Indian Society of Periodontology
Subjects:
Online Access:http://www.jisponline.com/article.asp?issn=0972-124X;year=2023;volume=27;issue=3;spage=295;epage=300;aulast=Elboraey
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author Mohamed Omar Elboraey
Sherouk Mohamed Gamal
author_facet Mohamed Omar Elboraey
Sherouk Mohamed Gamal
author_sort Mohamed Omar Elboraey
collection DOAJ
description Background: This clinical study aimed to overcome the difficulty of graft fixation and limited blood supply for dehiscence defects regeneration by using a cross-linked gelfoam matrix jointly with collagen membrane and xenograft. Materials and Methods: The study included twenty dehiscence-like defects in maxillary anterior teeth with ≥4 mm facial bone loss and ≥5 mm clinical attachment loss (CAL) in patients suffering from Stage III periodontitis. Sites were treated with regenerative surgery using a cross-linked gelfoam matrix with glutaraldehyde, xenograft, and collagen membrane. The recorded parameters were: CAL, probing pocket depth (PPD), and radiographic three-dimensional (3D) volume for dehiscence-like defects (3D volume of facial bone defects) and 3D volume of interproximal defects using cone-beam radiographs. Data of these parameters were collected at both baseline and 6 months postsurgery. “Paired t-test” was used to assess the two variables.” Results: Both CAL and PPD showed statistically significant reductions and there was a significant bone gain at 6 months postsurgery in comparison to baseline (P ≤ 0.05). Conclusion: Using a cross-linked gelfoam matrix with glutaraldehyde in combination with xenograft and collagen membrane could enhance the outcome of periodontal regeneration, especially in the treatment of challenging dehiscence defects.
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spelling doaj.art-0ef68865ceff41dea9d6b3cdab01909f2023-07-23T11:33:52ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Periodontology0972-124X2023-01-0127329530010.4103/jisp.jisp_312_22Clinical and radiographic study of the use of cross-linked gelfoam matrix in the treatment of dehiscence-like defects in Stage III periodontitisMohamed Omar ElboraeySherouk Mohamed GamalBackground: This clinical study aimed to overcome the difficulty of graft fixation and limited blood supply for dehiscence defects regeneration by using a cross-linked gelfoam matrix jointly with collagen membrane and xenograft. Materials and Methods: The study included twenty dehiscence-like defects in maxillary anterior teeth with ≥4 mm facial bone loss and ≥5 mm clinical attachment loss (CAL) in patients suffering from Stage III periodontitis. Sites were treated with regenerative surgery using a cross-linked gelfoam matrix with glutaraldehyde, xenograft, and collagen membrane. The recorded parameters were: CAL, probing pocket depth (PPD), and radiographic three-dimensional (3D) volume for dehiscence-like defects (3D volume of facial bone defects) and 3D volume of interproximal defects using cone-beam radiographs. Data of these parameters were collected at both baseline and 6 months postsurgery. “Paired t-test” was used to assess the two variables.” Results: Both CAL and PPD showed statistically significant reductions and there was a significant bone gain at 6 months postsurgery in comparison to baseline (P ≤ 0.05). Conclusion: Using a cross-linked gelfoam matrix with glutaraldehyde in combination with xenograft and collagen membrane could enhance the outcome of periodontal regeneration, especially in the treatment of challenging dehiscence defects.http://www.jisponline.com/article.asp?issn=0972-124X;year=2023;volume=27;issue=3;spage=295;epage=300;aulast=Elboraeycross-linked gel foam matrixdehiscence defectsperiodontal regenerationthree-dimensional volume
spellingShingle Mohamed Omar Elboraey
Sherouk Mohamed Gamal
Clinical and radiographic study of the use of cross-linked gelfoam matrix in the treatment of dehiscence-like defects in Stage III periodontitis
Journal of Indian Society of Periodontology
cross-linked gel foam matrix
dehiscence defects
periodontal regeneration
three-dimensional volume
title Clinical and radiographic study of the use of cross-linked gelfoam matrix in the treatment of dehiscence-like defects in Stage III periodontitis
title_full Clinical and radiographic study of the use of cross-linked gelfoam matrix in the treatment of dehiscence-like defects in Stage III periodontitis
title_fullStr Clinical and radiographic study of the use of cross-linked gelfoam matrix in the treatment of dehiscence-like defects in Stage III periodontitis
title_full_unstemmed Clinical and radiographic study of the use of cross-linked gelfoam matrix in the treatment of dehiscence-like defects in Stage III periodontitis
title_short Clinical and radiographic study of the use of cross-linked gelfoam matrix in the treatment of dehiscence-like defects in Stage III periodontitis
title_sort clinical and radiographic study of the use of cross linked gelfoam matrix in the treatment of dehiscence like defects in stage iii periodontitis
topic cross-linked gel foam matrix
dehiscence defects
periodontal regeneration
three-dimensional volume
url http://www.jisponline.com/article.asp?issn=0972-124X;year=2023;volume=27;issue=3;spage=295;epage=300;aulast=Elboraey
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AT sheroukmohamedgamal clinicalandradiographicstudyoftheuseofcrosslinkedgelfoammatrixinthetreatmentofdehiscencelikedefectsinstageiiiperiodontitis