Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common type of dementia that affects millions of individuals worldwide. It is an irreversible neurodegenerative disorder that is characterized by memory loss, impaired learning and thinking, and difficulty in performing regular daily activities. Despite nearly tw...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/12/2/415 |
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| author | Harsh Shah Fereshteh Dehghani Marjan Ramezan Ritchel B. Gannaban Zobayda Farzana Haque Fatemeh Rahimi Soheil Abbasi Andrew C. Shin |
| author_facet | Harsh Shah Fereshteh Dehghani Marjan Ramezan Ritchel B. Gannaban Zobayda Farzana Haque Fatemeh Rahimi Soheil Abbasi Andrew C. Shin |
| author_sort | Harsh Shah |
| collection | DOAJ |
| description | Alzheimer’s disease (AD) is the most common type of dementia that affects millions of individuals worldwide. It is an irreversible neurodegenerative disorder that is characterized by memory loss, impaired learning and thinking, and difficulty in performing regular daily activities. Despite nearly two decades of collective efforts to develop novel medications that can prevent or halt the disease progression, we remain faced with only a few options with limited effectiveness. There has been a recent growth of interest in the role of nutrition in brain health as we begin to gain a better understanding of what and how nutrients affect hormonal and neural actions that not only can lead to typical cardiovascular or metabolic diseases but also an array of neurological and psychiatric disorders. Vitamins and minerals, also known as micronutrients, are elements that are indispensable for functions including nutrient metabolism, immune surveillance, cell development, neurotransmission, and antioxidant and anti-inflammatory properties. In this review, we provide an overview on some of the most common vitamins and minerals and discuss what current studies have revealed on the link between these essential micronutrients and cognitive performance or AD. |
| first_indexed | 2024-03-11T09:13:43Z |
| format | Article |
| id | doaj.art-0ef6d6ec48e74540829a3137bd260423 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-11T09:13:43Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-0ef6d6ec48e74540829a3137bd2604232023-11-16T18:47:52ZengMDPI AGAntioxidants2076-39212023-02-0112241510.3390/antiox12020415Revisiting the Role of Vitamins and Minerals in Alzheimer’s DiseaseHarsh Shah0Fereshteh Dehghani1Marjan Ramezan2Ritchel B. Gannaban3Zobayda Farzana Haque4Fatemeh Rahimi5Soheil Abbasi6Andrew C. Shin7Neurobiology of Nutrition Laboratory, Department of Nutritional Sciences, College of Human Sciences, Texas Tech University, Lubbock, TX 79409, USANeurobiology of Nutrition Laboratory, Department of Nutritional Sciences, College of Human Sciences, Texas Tech University, Lubbock, TX 79409, USANeurobiology of Nutrition Laboratory, Department of Nutritional Sciences, College of Human Sciences, Texas Tech University, Lubbock, TX 79409, USANeurobiology of Nutrition Laboratory, Department of Nutritional Sciences, College of Human Sciences, Texas Tech University, Lubbock, TX 79409, USANeurobiology of Nutrition Laboratory, Department of Nutritional Sciences, College of Human Sciences, Texas Tech University, Lubbock, TX 79409, USADepartment of Nutritional Sciences, School of Nutrition and Food Sciences, Kermanshah University of Medical Sciences, Kermanshah 67158-47141, IranDepartment of Nutritional Sciences, School of Nutrition and Food Sciences, Kermanshah University of Medical Sciences, Kermanshah 67158-47141, IranNeurobiology of Nutrition Laboratory, Department of Nutritional Sciences, College of Human Sciences, Texas Tech University, Lubbock, TX 79409, USAAlzheimer’s disease (AD) is the most common type of dementia that affects millions of individuals worldwide. It is an irreversible neurodegenerative disorder that is characterized by memory loss, impaired learning and thinking, and difficulty in performing regular daily activities. Despite nearly two decades of collective efforts to develop novel medications that can prevent or halt the disease progression, we remain faced with only a few options with limited effectiveness. There has been a recent growth of interest in the role of nutrition in brain health as we begin to gain a better understanding of what and how nutrients affect hormonal and neural actions that not only can lead to typical cardiovascular or metabolic diseases but also an array of neurological and psychiatric disorders. Vitamins and minerals, also known as micronutrients, are elements that are indispensable for functions including nutrient metabolism, immune surveillance, cell development, neurotransmission, and antioxidant and anti-inflammatory properties. In this review, we provide an overview on some of the most common vitamins and minerals and discuss what current studies have revealed on the link between these essential micronutrients and cognitive performance or AD.https://www.mdpi.com/2076-3921/12/2/415essential micronutrientsantioxidantsanti-inflammatoryamyloidTaucognitive function |
| spellingShingle | Harsh Shah Fereshteh Dehghani Marjan Ramezan Ritchel B. Gannaban Zobayda Farzana Haque Fatemeh Rahimi Soheil Abbasi Andrew C. Shin Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease Antioxidants essential micronutrients antioxidants anti-inflammatory amyloid Tau cognitive function |
| title | Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease |
| title_full | Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease |
| title_fullStr | Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease |
| title_full_unstemmed | Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease |
| title_short | Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease |
| title_sort | revisiting the role of vitamins and minerals in alzheimer s disease |
| topic | essential micronutrients antioxidants anti-inflammatory amyloid Tau cognitive function |
| url | https://www.mdpi.com/2076-3921/12/2/415 |
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