Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1
Leukocyte adhesion deficiency type 1 (LAD-1) is a rare autosomal recessive immunodeficiency disorder, characterized by recurrent bacterial and fungal infections without pus formation. Herein, we report a case of LAD-1 that developed into gastrointestinal cytomegalovirus (CMV) disease and manifested...
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Format: | Article |
Language: | English |
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Tehran University of Medical Sciences
2018-11-01
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Series: | Acta Medica Iranica |
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Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/6487 |
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author | Ahmad Bahrami Mahnaz Sadeghian Mehrdad Sheikhvatan Arash Foroudi Sara Harsini Nima Rezaei |
author_facet | Ahmad Bahrami Mahnaz Sadeghian Mehrdad Sheikhvatan Arash Foroudi Sara Harsini Nima Rezaei |
author_sort | Ahmad Bahrami |
collection | DOAJ |
description | Leukocyte adhesion deficiency type 1 (LAD-1) is a rare autosomal recessive immunodeficiency disorder, characterized by recurrent bacterial and fungal infections without pus formation. Herein, we report a case of LAD-1 that developed into gastrointestinal cytomegalovirus (CMV) disease and manifested with persistent abdominal pain and bloody diarrhea. Although the presence of concurrent gastrointestinal CMV infection with LAD-1 is a rare condition, this case highlights the need for further research to evaluate the complex mechanisms between LAD-1 and CMV occurrence. |
first_indexed | 2024-12-12T04:18:55Z |
format | Article |
id | doaj.art-0efb08c0112e43cd9ab3488898b551fd |
institution | Directory Open Access Journal |
issn | 0044-6025 1735-9694 |
language | English |
last_indexed | 2024-12-12T04:18:55Z |
publishDate | 2018-11-01 |
publisher | Tehran University of Medical Sciences |
record_format | Article |
series | Acta Medica Iranica |
spelling | doaj.art-0efb08c0112e43cd9ab3488898b551fd2022-12-22T00:38:23ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942018-11-015686487Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1Ahmad Bahrami0Mahnaz Sadeghian1Mehrdad Sheikhvatan2Arash Foroudi3Sara Harsini4Nima Rezaei5Department of Allergy, Ali-Asghar Children’s Hospital, Iran University of Medical Sciences, Tehran, Iran.Department of Pediatrics, Ali-Asghar Hospital, Iran University of Medical Sciences, Tehran, Iran.Research and Development, Iran University of Medical Sciences, Tehran, Iran.Department of Allergy, Ali-Asghar Children’s Hospital, Iran University of Medical Sciences, Tehran, Iran.Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. AND Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran.Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. AND Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran. AND Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.Leukocyte adhesion deficiency type 1 (LAD-1) is a rare autosomal recessive immunodeficiency disorder, characterized by recurrent bacterial and fungal infections without pus formation. Herein, we report a case of LAD-1 that developed into gastrointestinal cytomegalovirus (CMV) disease and manifested with persistent abdominal pain and bloody diarrhea. Although the presence of concurrent gastrointestinal CMV infection with LAD-1 is a rare condition, this case highlights the need for further research to evaluate the complex mechanisms between LAD-1 and CMV occurrence.https://acta.tums.ac.ir/index.php/acta/article/view/6487CytomegalovirusLeukocyte adhesion deficiency type 1Gastrointestinal tractChildren |
spellingShingle | Ahmad Bahrami Mahnaz Sadeghian Mehrdad Sheikhvatan Arash Foroudi Sara Harsini Nima Rezaei Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1 Acta Medica Iranica Cytomegalovirus Leukocyte adhesion deficiency type 1 Gastrointestinal tract Children |
title | Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1 |
title_full | Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1 |
title_fullStr | Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1 |
title_full_unstemmed | Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1 |
title_short | Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1 |
title_sort | cytomegalovirus infection in a patient with leukocyte adhesion deficiency type 1 |
topic | Cytomegalovirus Leukocyte adhesion deficiency type 1 Gastrointestinal tract Children |
url | https://acta.tums.ac.ir/index.php/acta/article/view/6487 |
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