Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1

Leukocyte adhesion deficiency type 1 (LAD-1) is a rare autosomal recessive immunodeficiency disorder, characterized by recurrent bacterial and fungal infections without pus formation. Herein, we report a case of LAD-1 that developed into gastrointestinal cytomegalovirus (CMV) disease and manifested...

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Main Authors: Ahmad Bahrami, Mahnaz Sadeghian, Mehrdad Sheikhvatan, Arash Foroudi, Sara Harsini, Nima Rezaei
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2018-11-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/6487
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author Ahmad Bahrami
Mahnaz Sadeghian
Mehrdad Sheikhvatan
Arash Foroudi
Sara Harsini
Nima Rezaei
author_facet Ahmad Bahrami
Mahnaz Sadeghian
Mehrdad Sheikhvatan
Arash Foroudi
Sara Harsini
Nima Rezaei
author_sort Ahmad Bahrami
collection DOAJ
description Leukocyte adhesion deficiency type 1 (LAD-1) is a rare autosomal recessive immunodeficiency disorder, characterized by recurrent bacterial and fungal infections without pus formation. Herein, we report a case of LAD-1 that developed into gastrointestinal cytomegalovirus (CMV) disease and manifested with persistent abdominal pain and bloody diarrhea. Although the presence of concurrent gastrointestinal CMV infection with LAD-1 is a rare condition, this case highlights the need for further research to evaluate the complex mechanisms between LAD-1 and CMV occurrence.
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spelling doaj.art-0efb08c0112e43cd9ab3488898b551fd2022-12-22T00:38:23ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942018-11-015686487Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1Ahmad Bahrami0Mahnaz Sadeghian1Mehrdad Sheikhvatan2Arash Foroudi3Sara Harsini4Nima Rezaei5Department of Allergy, Ali-Asghar Children’s Hospital, Iran University of Medical Sciences, Tehran, Iran.Department of Pediatrics, Ali-Asghar Hospital, Iran University of Medical Sciences, Tehran, Iran.Research and Development, Iran University of Medical Sciences, Tehran, Iran.Department of Allergy, Ali-Asghar Children’s Hospital, Iran University of Medical Sciences, Tehran, Iran.Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. AND Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran.Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. AND Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran. AND Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.Leukocyte adhesion deficiency type 1 (LAD-1) is a rare autosomal recessive immunodeficiency disorder, characterized by recurrent bacterial and fungal infections without pus formation. Herein, we report a case of LAD-1 that developed into gastrointestinal cytomegalovirus (CMV) disease and manifested with persistent abdominal pain and bloody diarrhea. Although the presence of concurrent gastrointestinal CMV infection with LAD-1 is a rare condition, this case highlights the need for further research to evaluate the complex mechanisms between LAD-1 and CMV occurrence.https://acta.tums.ac.ir/index.php/acta/article/view/6487CytomegalovirusLeukocyte adhesion deficiency type 1Gastrointestinal tractChildren
spellingShingle Ahmad Bahrami
Mahnaz Sadeghian
Mehrdad Sheikhvatan
Arash Foroudi
Sara Harsini
Nima Rezaei
Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1
Acta Medica Iranica
Cytomegalovirus
Leukocyte adhesion deficiency type 1
Gastrointestinal tract
Children
title Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1
title_full Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1
title_fullStr Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1
title_full_unstemmed Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1
title_short Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1
title_sort cytomegalovirus infection in a patient with leukocyte adhesion deficiency type 1
topic Cytomegalovirus
Leukocyte adhesion deficiency type 1
Gastrointestinal tract
Children
url https://acta.tums.ac.ir/index.php/acta/article/view/6487
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